| Literature DB >> 24290382 |
Brent Wilkinson1, Daniel B Campbell.
Abstract
Accumulating evidence indicates that long noncoding RNAs (lncRNAs) contribute to autism spectrum disorder (ASD) risk. Although a few lncRNAs have long been recognized to have important functions, the vast majority of this class of molecules remains uncharacterized. Because lncRNAs are more abundant in human brain than protein-coding RNAs, it is likely that they contribute to brain disorders, including ASD. We review here the known functions of lncRNAs and the potential contributions of lncRNAs to ASD.Entities:
Keywords: Biomarkers; Epigenetics; Gene regulation; Long noncoding RNA; Noncoding RNA; Transcriptional regulation; lncRNA; ncRNA
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Year: 2013 PMID: 24290382 DOI: 10.1016/B978-0-12-418700-9.00002-2
Source DB: PubMed Journal: Int Rev Neurobiol ISSN: 0074-7742 Impact factor: 3.230