Literature DB >> 24288729

Study of hepatoprotective effects of xymedon.

A B Vyshtakalyuk1, N G Nazarov, I V Zueva, A V Lantsova, O A Minnekhanova, D V Busygin, A G Porfiryev, V G Evtyugin, V S Reznik, V V Zobov.   

Abstract

Xymedon (1-(β-oxyethyl)-4,6-dimethyl-1,2-dihydro-2-oxopyrimidine), a regeneratory and wound-healing drug, exhibited hepatoprotective activity in laboratory animals with experimental toxic hepatitis. Oral drug reduced the severity of toxic involvement of the liver induced by CCl4 and reduced animal mortality. Xymedon promoted recovery of the blood biochemical parameters characterizing the liver status.

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Year:  2013        PMID: 24288729     DOI: 10.1007/s10517-013-2215-0

Source DB:  PubMed          Journal:  Bull Exp Biol Med        ISSN: 0007-4888            Impact factor:   0.804


  1 in total

1.  Synthesis and antihepatotoxic activity of dihydropyrimidinone derivatives linked with 1,4-benzodioxane.

Authors:  Mashooq Ahmad Bhat; Mohamed A Al-Omar; Azmat Ali Khan; Amer M Alanazi; Ahmed M Naglah
Journal:  Drug Des Devel Ther       Date:  2019-07-18       Impact factor: 4.162

  1 in total

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