Literature DB >> 24288398

Paediatric post-septal and pre-septal cellulitis: 10 years' experience at a tertiary-level children's hospital.

A V Mathew1, E Craig, R Al-Mahmoud, R Batty, A Raghavan, S R Mordekar, J Chan, D J A Connolly.   

Abstract

OBJECTIVE: To assess the incidence and complications of pre-septal (pre-SC) and post-septal (post-SC) cellulitis over 10 years. Pre-SC and post-SC are also known as periorbital and orbital cellulitis, respectively.
METHODS: Retrospective analysis of CT scans. Data included the presence of pre-SC and post-SC, paranasal sinus disease (PNS) and complications.
RESULTS: Among 125 patients scanned for these suspected diagnoses, 67 had both pre-SC and post-SC, 37 had pre-SC and 4 had post-SC; there were 17 normal scans. 110 patients had PNS. 68/71 (96%) patients with post-SC had PNS. Post-SC complications included orbital and/or subperiosteal abscess (50/71: 30 medial orbital, 10 superomedial, 3 lateral, 2 anteromedial, 2 inferomedial, 1 superior, 1 anterosuperior and 1 not specified), cavernous sinus thrombosis (CST) (1), superior ophthalmic vein (SOV) thrombosis (4) and subdural frontal empyema (2); 1 patient had SOV and CST and subdural empyema.
CONCLUSION: 71/125 (57%) patients had post-SC. 50/125 (40%) patients imaged for pre-SC/post-SC had orbital abscess; 44/50 (88%) of these involved the medial orbit. Patients can develop solely superior or inferior abscesses that are difficult to identify by axial imaging alone, hence coronal reformatted imaging is essential. 5/125 (4%) patients developed major complications (SOV/CST/empyema), hence imaging review of the head and cavernous sinus region is essential. A diagnosis of post-SC on CT should alert the radiologist because this diagnosis can be associated with an increased incidence (5/71, 7%) of complications. ADVANCES IN KNOWLEDGE: We recommend that all patients with a suspected diagnosis of post-SC should undergo CT scan (post-contrast orbits and post-contrast head, with multiplanar reformats and a careful review of the SOV and the cavernous sinus). Particular attention should be paid to exclude intracranial complications including subdural empyema and cerebral abscess. As soon as a diagnosis of post-SC is made, in addition to informing the referring clinical team, urgent opinion should be sought from ear, nose and throat (ENT), neurology and ophthalmology with a view to urgently drain of the paranasal sinuses`.

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Mesh:

Year:  2013        PMID: 24288398      PMCID: PMC3898973          DOI: 10.1259/bjr.20130503

Source DB:  PubMed          Journal:  Br J Radiol        ISSN: 0007-1285            Impact factor:   3.039


  8 in total

Review 1.  Periorbital versus orbital cellulitis.

Authors:  Laurence B Givner
Journal:  Pediatr Infect Dis J       Date:  2002-12       Impact factor: 2.129

Review 2.  Guidelines for the management of periorbital cellulitis/abscess.

Authors:  L Howe; N S Jones
Journal:  Clin Otolaryngol Allied Sci       Date:  2004-12

3.  MR imaging of orbital inflammatory syndrome, orbital cellulitis, and orbital lymphoid lesions: the role of diffusion-weighted imaging.

Authors:  R Kapur; A R Sepahdari; M F Mafee; A M Putterman; V Aakalu; L J A Wendel; P Setabutr
Journal:  AJNR Am J Neuroradiol       Date:  2008-10-08       Impact factor: 3.825

4.  MRI of orbital cellulitis and orbital abscess: the role of diffusion-weighted imaging.

Authors:  Ali R Sepahdari; Vinay K Aakalu; Rashmi Kapur; Edward A Michals; Nitu Saran; Adam French; Mahmood F Mafee
Journal:  AJR Am J Roentgenol       Date:  2009-09       Impact factor: 3.959

Review 5.  An evidence based review of periorbital cellulitis.

Authors:  D E C Baring; O J Hilmi
Journal:  Clin Otolaryngol       Date:  2011-02       Impact factor: 2.597

6.  Current treatment and outcome in orbital cellulitis.

Authors:  M P Ferguson; A A McNab
Journal:  Aust N Z J Ophthalmol       Date:  1999-12

7.  The pathogenesis of orbital complications in acute sinusitis.

Authors:  J R Chandler; D J Langenbrunner; E R Stevens
Journal:  Laryngoscope       Date:  1970-09       Impact factor: 3.325

8.  Acute periorbital infections: who needs emergent imaging?

Authors:  Tiffany F Rudloe; Marvin B Harper; Sanjay P Prabhu; Reza Rahbar; Deborah Vanderveen; Amir A Kimia
Journal:  Pediatrics       Date:  2010-03-01       Impact factor: 7.124

  8 in total
  4 in total

Review 1.  Applying Pharmacodynamics and Antimicrobial Stewardship to Pediatric Preseptal and Orbital Cellulitis.

Authors:  Grant T Stimes; Jennifer E Girotto
Journal:  Paediatr Drugs       Date:  2019-12       Impact factor: 3.022

Review 2.  Epidemiology and Management of Orbital Cellulitis in Children.

Authors:  Brenda I Anosike; Veena Ganapathy; Mari M Nakamura
Journal:  J Pediatric Infect Dis Soc       Date:  2022-05-30       Impact factor: 5.235

3.  Orbital Cellulitis: Defining Multidisciplinary Approach as the Need of the Hour.

Authors:  Semridhi Gupta; Shivam Sharma
Journal:  Indian J Otolaryngol Head Neck Surg       Date:  2019-03-16

4.  Coronavirus Disease 2019 as a Possible Cause of Severe Orbital Cellulitis.

Authors:  Vinicius Almeida Carvalho; Vinícius Eduardo de Oliveira Vergínio; Gabriel Conceição Brito; Cecilia Luiz Pereira-Stabile; Glaykon Alex Vitti Stabile
Journal:  J Craniofac Surg       Date:  2021 Nov-Dec 01       Impact factor: 1.172

  4 in total

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