Literature DB >> 24287485

Pneumocystis jerovecii pneumonia in a patient with untreated chronic lymphocytic leukaemia: a novel case and postulations concerning the mechanism.

Alexandros Kalkanis1, Marc A Judson, Mark B Napier.   

Abstract

Chronic lymphocytic leukaemia (CLL), even when severe, is not directly associated with opportunistic infections. Opportunistic infections that occur with CLL are almost exclusively related to immunosuppression caused by chemotherapeutic drugs used to treat CLL. We report a case of Pneumocystis jirovecii (PJ) pneumonia that occurred in a patient with untreated CLL with pulmonary involvement. We suspect that PJ pneumonia resulted from an inadequate immune response in the lung parenchyma resulting from excessive local accumulation of CLL cells.

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Year:  2013        PMID： 24287485      PMCID： PMC3847474          DOI： 10.1136/bcr-2013-202124

Source DB:  PubMed          Journal:  BMJ Case Rep        ISSN： 1757-790X


  8 in total

1.  Summary of the Guidelines for Preventing Opportunistic Infections among Hematopoietic Stem Cell Transplant Recipients.

Authors:  C A Dykewicz
Journal:  Clin Infect Dis       Date:  2001-06-14       Impact factor: 9.079

2.  Pneumocystis carinii pneumonia in patients with hematologic malignancies: a descriptive study.

Authors:  F Roblot; G Le Moal; C Godet; P Hutin; M Texereau; E Boyer; T Prazuck; C Lacroix; M Faouzi Souala; F Raffi; P Weinbreck; J M Besnier; B Garo; L de Gentile; B Becq-Giraudon
Journal:  J Infect       Date:  2003-07       Impact factor: 6.072

3.  Transmission of Pneumocystis carinii DNA from a patient with P. carinii pneumonia to immunocompetent contact health care workers.

Authors:  S L Vargas; C A Ponce; F Gigliotti; A V Ulloa; S Prieto; M P Muñoz; W T Hughes
Journal:  J Clin Microbiol       Date:  2000-04       Impact factor: 5.948

4.  Pneumocystis carinii f. sp. hominis DNA in immunocompetent health care workers in contact with patients with P. carinii pneumonia.

Authors:  R F Miller; H E Ambrose; A E Wakefield
Journal:  J Clin Microbiol       Date:  2001-11       Impact factor: 5.948

Review 5.  Infectious complications of chronic lymphocytic leukemia.

Authors:  Punit D Wadhwa; Vicki A Morrison
Journal:  Semin Oncol       Date:  2006-04       Impact factor: 4.929

6.  Serologic responses to Pneumocystis carinii antigens in health and disease.

Authors:  S L Peglow; A G Smulian; M J Linke; C L Pogue; S Nurre; J Crisler; J Phair; J W Gold; D Armstrong; P D Walzer
Journal:  J Infect Dis       Date:  1990-02       Impact factor: 5.226

7.  Pneumocystis carinii infection: evidence for high prevalence in normal and immunosuppressed children.

Authors:  L L Pifer; W T Hughes; S Stagno; D Woods
Journal:  Pediatrics       Date:  1978-01       Impact factor: 7.124

8.  Pneumocystis colonization is highly prevalent in the autopsied lungs of the general population.

Authors:  Carolina A Ponce; Myriam Gallo; Rebeca Bustamante; Sergio L Vargas
Journal:  Clin Infect Dis       Date:  2010-02-01       Impact factor: 9.079
  8 in total
  2 in total

1.  Pneumocystis jirovecii Pneumonia in a Treatment-Naive Patient With Chronic Lymphocytic Leukemia.

Authors:  Jeffrey R Strich; Theresa D Jerussi; Adrian Wiestner; Steven M Holland
Journal:  Infect Dis Clin Pract (Baltim Md)       Date:  2016-11

2.  Atypical Pneumocystis jirovecii pneumonia in previously untreated patients with CLL on single-agent ibrutinib.

Authors:  Inhye E Ahn; Theresa Jerussi; Mohammed Farooqui; Xin Tian; Adrian Wiestner; Juan Gea-Banacloche
Journal:  Blood       Date:  2016-08-08       Impact factor: 22.113
  2 in total

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