Diabetic retinopathy: current concepts and emerging therapy.

More Americans become blind each year from microvascular complications of diabetes than from any other cause. Several studies have indicated that tight glucose control and lifestyle modification can dramatically reduce the incidence and prevalence of diabetic retinopathy. Research over the past several years has yielded a tremendous increase in our knowledge of the pathogenesis of the damage to the retina that occurs in diabetes and has facilitated our ability to intervene and control the damage. New intravitreal medical therapies supported by government- and industry-supported research are gradually replacing standard laser photocoagulation for the treatment of all forms of retinopathy.