Literature DB >> 24286770

Azoospermia due to spermatogenic failure.

Boback M Berookhim1, Peter N Schlegel.   

Abstract

This article summarizes the current literature regarding azoospermia caused by spermatogenic failure. The causes and genetic contributions to spermatogenic failure are reviewed. Medical therapies including use of hormonal manipulation, whether guided by a specific abnormality or empiric, to induce spermatogenesis are discussed. The role of surgical therapy, including a discussion of varicocelectomy in men with spermatogenic failure, as well as an in-depth review of surgical sperm retrieval with testicular sperm extraction and microdissection testicular sperm extraction, is provided. Finally, future directions of treatment for men with spermatogenic failure are discussed, namely, stem cell and gene therapy.
Copyright © 2014 Elsevier Inc. All rights reserved.

Entities:  

Keywords:  Genetics; Male infertility; Medical therapy; Microdissection-TESE (microTESE); Nonobstructive azoospermia; Testicular sperm extraction

Mesh：

Year:  2013        PMID： 24286770     DOI： 10.1016/j.ucl.2013.08.004

Source DB:  PubMed          Journal:  Urol Clin North Am        ISSN： 0094-0143            Impact factor:   2.241


  18 in total

1.  Testis specific serine/threonine protein kinase 4 (TSSK4) leads to cell apoptosis relying on its kinase activity.

Authors:  Xiao-Li Wang; You-Heng Wei; Guo-Long Fu; Long Yu
Journal:  J Huazhong Univ Sci Technolog Med Sci       Date:  2015-04-16

Review 2.  Management of non-obstructive azoospermia.

Authors:  Koji Chiba; Noritoshi Enatsu; Masato Fujisawa
Journal:  Reprod Med Biol       Date:  2016-01-18

Review 3.  [Testicular sperm extraction in male infertility : Indications, success rates, practical implementation, and possible complications].

Authors:  J Rosellen; J Steffens; J Kranz
Journal:  Urologe A       Date:  2021-03-03       Impact factor: 0.639

Review 4.  Varicocele and testicular function.

Authors:  Alexander W Pastuszak; Run Wang
Journal:  Asian J Androl       Date:  2015 Jul-Aug       Impact factor: 3.285

5.  Potential spermatogenesis recovery with bone marrow mesenchymal stem cells in an azoospermic rat model.

Authors:  Deying Zhang; Xing Liu; Jinpu Peng; Dawei He; Tao Lin; Jing Zhu; Xuliang Li; Yuanyuan Zhang; Guanghui Wei
Journal:  Int J Mol Sci       Date:  2014-07-24       Impact factor: 5.923

6.  Histomorphometric evaluation of treatment of rat azoosper-mic seminiferous tubules by allotransplantation of bone marrow-derived mesenchymal stem cells.

Authors:  Farhad Rahmanifar; Amin Tamadon; Davood Mehrabani; Shahrokh Zare; Sorush Abasi; Saeideh Keshavarz; Mehdi Dianatpour; Zahra Khodabandeh; Iman Raze Ghian Jahromi; Omid Koohi-Hoseinabadi
Journal:  Iran J Basic Med Sci       Date:  2016-06       Impact factor: 2.699

Review 7.  The varicocele: diagnostic dilemmas, therapeutic challenges and future perspectives.

Authors:  Koji Chiba; Ranjith Ramasamy; Dolores J Lamb; Larry I Lipshultz
Journal:  Asian J Androl       Date:  2016 Mar-Apr       Impact factor: 3.285

Review 8.  Recent advances in the genetics of testicular failure.

Authors:  Seung-Hun Song; Koji Chiba; Ranjith Ramasamy; Dolores J Lamb
Journal:  Asian J Androl       Date:  2016 May-Jun       Impact factor: 3.285

9.  Induction of Spermatogenesis by Bone Marrow-derived Mesenchymal Stem Cells in Busulfan-induced Azoospermia in Hamster.

Authors:  Amin Tamadon; Davood Mehrabani; Farhad Rahmanifar; Alireza Raayat Jahromi; Mohadeseh Panahi; Shahrokh Zare; Zahra Khodabandeh; Iman Razeghian Jahromi; Nader Tanideh; Mehdi Dianatpour; Mani Ramzi; Omid Koohi-Hoseinabadi
Journal:  Int J Stem Cells       Date:  2015-11       Impact factor: 2.500

10.  The Regenerative Effect of Bone Marrow-Derived Stem Cells in Spermatogenesis of Infertile Hamster.

Authors:  Akbar Vahdati; Alireza Fathi; Mehrdokht Hajihoseini; Ghaem Aliborzi; Ebrahim Hosseini
Journal:  World J Plast Surg       Date:  2017-01
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