Literature DB >> 24286573

Methotrexate: new uses for an old drug.

Philip J Hashkes1, Mara L Becker2, David A Cabral3, Ronald M Laxer4, Amy S Paller5, C Egla Rabinovich6, Dan Turner7, Francesco Zulian8.   

Abstract

Entities:  

Keywords:  AICAR; Amino-imidazole carboxamide ribonucleotide; CD; Crohn's disease; GPA; Granulomatosis with polyangiitis; IBD; Inflammatory bowel disease; JIA; Juvenile idiopathic arthritis; MRP; MTX; Methotrexate; Myeloid-related protein; SNP; Single nucleotide polymorphism

Mesh:

Substances:

Year:  2013        PMID: 24286573     DOI: 10.1016/j.jpeds.2013.10.029

Source DB:  PubMed          Journal:  J Pediatr        ISSN: 0022-3476            Impact factor:   4.406


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  19 in total

1.  Drugs and drug-like molecules can modulate the function of mucosal-associated invariant T cells.

Authors:  Andrew N Keller; Sidonia B G Eckle; Weijun Xu; Ligong Liu; Victoria A Hughes; Jeffrey Y W Mak; Bronwyn S Meehan; Troi Pediongco; Richard W Birkinshaw; Zhenjun Chen; Huimeng Wang; Criselle D'Souza; Lars Kjer-Nielsen; Nicholas A Gherardin; Dale I Godfrey; Lyudmila Kostenko; Alexandra J Corbett; Anthony W Purcell; David P Fairlie; James McCluskey; Jamie Rossjohn
Journal:  Nat Immunol       Date:  2017-02-06       Impact factor: 25.606

Review 2.  In the Pursuit of Methotrexate Treatment Response Biomarker in Juvenile Idiopathic Arthritis-Are We Getting Closer to Personalised Medicine?

Authors:  Justyna Roszkiewicz; Elzbieta Smolewska
Journal:  Curr Rheumatol Rep       Date:  2017-04       Impact factor: 4.592

3.  Toward resolving the catalytic mechanism of dihydrofolate reductase using neutron and ultrahigh-resolution X-ray crystallography.

Authors:  Qun Wan; Brad C Bennett; Mark A Wilson; Andrey Kovalevsky; Paul Langan; Elizabeth E Howell; Chris Dealwis
Journal:  Proc Natl Acad Sci U S A       Date:  2014-12-01       Impact factor: 11.205

Review 4.  Distal Regions Regulate Dihydrofolate Reductase-Ligand Interactions.

Authors:  Melanie Goldstein; Nina M Goodey
Journal:  Methods Mol Biol       Date:  2021

Review 5.  Therapeutic role of methotrexate in pediatric Crohn's disease.

Authors:  Zlatko Djurić; Ljiljana Šaranac; Ivana Budić; Voja Pavlović; Jelena Djordjević
Journal:  Bosn J Basic Med Sci       Date:  2018-08-01       Impact factor: 3.363

6.  A randomized controlled trial of methotrexate for patients with generalized myasthenia gravis.

Authors:  Mamatha Pasnoor; Jianghua He; Laura Herbelin; Ted M Burns; Sharon Nations; Vera Bril; Annabel K Wang; Bakri H Elsheikh; John T Kissel; David Saperstein; J Aziz Shaibani; Carlayne Jackson; Andrea Swenson; James F Howard; Namita Goyal; William David; Matthew Wicklund; Michael Pulley; Mara Becker; Tahseen Mozaffar; Michael Benatar; Robert Pazcuzzi; Ericka Simpson; Jeffrey Rosenfeld; Mazen M Dimachkie; Jeffrey M Statland; Richard J Barohn
Journal:  Neurology       Date:  2016-06-15       Impact factor: 9.910

Review 7.  Progressive hemifacial atrophy: a review.

Authors:  Stanislav N Tolkachjov; Nirav G Patel; Megha M Tollefson
Journal:  Orphanet J Rare Dis       Date:  2015-04-01       Impact factor: 4.123

8.  Methotrexate Promotes Platelet Apoptosis via JNK-Mediated Mitochondrial Damage: Alleviation by N-Acetylcysteine and N-Acetylcysteine Amide.

Authors:  Manoj Paul; Mahadevappa Hemshekhar; Ram M Thushara; Mahalingam S Sundaram; Somanathapura K NaveenKumar; Shivanna Naveen; Sannaningaiah Devaraja; Kumar Somyajit; Robert West; Siddaiah C Nayaka; Uzma I Zakai; Ganesh Nagaraju; Kanchugarakoppal S Rangappa; Kempaiah Kemparaju; Kesturu S Girish
Journal:  PLoS One       Date:  2015-06-17       Impact factor: 3.240

Review 9.  Psoriasis in Children and Adolescents: Diagnosis, Management and Comorbidities.

Authors:  I M G J Bronckers; A S Paller; M J van Geel; P C M van de Kerkhof; M M B Seyger
Journal:  Paediatr Drugs       Date:  2015-10       Impact factor: 3.022

10.  Rutin attenuates intestinal toxicity induced by Methotrexate linked with anti-oxidative and anti-inflammatory effects.

Authors:  Raju Gautam; Manjari Singh; Swetlana Gautam; Jitendra Kumar Rawat; Shubhini A Saraf; Gaurav Kaithwas
Journal:  BMC Complement Altern Med       Date:  2016-03-10       Impact factor: 3.659

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