Comparison of fiber optical and video monitor stimulators in normals and multiple sclerosis patients.

A comparison of VEP findings using a fiber optical stimulator with three color combinations (black/red, black/green and red/green) and a conventional video monitor stimulator in black/white was performed in 3 groups of subjects: a group with definite lesions in the visual pathway, a group with suspected lesions and a control group. No significant correlations of P100 latency were found in the normative group, probably because of the small range of their values. All correlations were significant in the two patient groups, except for the red/green stimuli in the definite group. In general, the red/green combination was inferior to other color combinations in eliciting VEPs. The patient groups with definite, as well as suspected, lesions indicated no benefit from the color stimuli, as compared with black/white. The major advantage of the fiber optical stimulator is its simplicity, the lack of stimulus artifacts and the accessibility to the patient's bed side, thanks to its small size. Stimulators with higher illuminance and improved pattern element shape should narrow the still unacceptable normative variability of the wave forms recorded.