Literature DB >> 24285325

Positron emission tomography radioligands for the opioid system.

Robert F Dannals1.   

Abstract

Opiate receptors are found in the brain, the spinal cord, some peripheral sensory neurons, and the gastrointestinal tract. Naturally occurring and synthetic opiate ligands exert their influence on a wide variety of processes including analgesia, euphoria, dysphoria, sedation, respiratory depression, and miosis and are frequently topics for discussions on addiction and physical dependence. This review looks at the history of positron emission tomography radioligands for probing this receptor system.
Copyright © 2013 John Wiley & Sons, Ltd.

Entities:  

Keywords:  fluorine-18; neuroreceptor; opiate; receptor

Mesh：

Substances：

Year:  2013        PMID： 24285325     DOI： 10.1002/jlcr.3005

Source DB:  PubMed          Journal:  J Labelled Comp Radiopharm        ISSN： 0362-4803            Impact factor:   1.921


  7 in total

1.  Design, synthesis and evaluation of 111In labeled DOTA-conjugated tetrapeptides having high affinity and selectivity for mu opioid receptors.

Authors:  John R Lever; Emily A Fergason-Cantrell; Terry L Carmack; Lisa D Watkinson; Fabio Gallazzi
Journal:  Nucl Med Biol       Date:  2019-03-07       Impact factor: 2.408

2.  Synthesis and opioid receptor binding of indium (III) and [111In]-labeled macrocyclic conjugates of diprenorphine: novel ligands designed for imaging studies of peripheral opioid receptors.

Authors:  Shefali Srivastava; Emily A Fergason-Cantrell; Roger I Nahas; John R Lever
Journal:  Tetrahedron       Date:  2016-08-04       Impact factor: 2.457

3.  An Improved Antagonist Radiotracer for the κ-Opioid Receptor: Synthesis and Characterization of (11)C-LY2459989.

Authors:  Ming-Qiang Zheng; Su Jin Kim; Daniel Holden; Shu-fei Lin; Anne Need; Karen Rash; Vanessa Barth; Charles Mitch; Antonio Navarro; Michael Kapinos; Kathleen Maloney; Jim Ropchan; Richard E Carson; Yiyun Huang
Journal:  J Nucl Med       Date:  2014-05-22       Impact factor: 10.057

Review 4.  Diels-Alder Adducts of Morphinan-6,8-Dienes and Their Transformations.

Authors:  János Marton; Anikó Fekete; Paul Cumming; Sándor Hosztafi; Pál Mikecz; Gjermund Henriksen
Journal:  Molecules       Date:  2022-04-30       Impact factor: 4.927

5.  Automated radiochemical synthesis and biodistribution of [¹¹C]l-α-acetylmethadol ([¹¹C]LAAM).

Authors:  Kiran Kumar Solingapuram Sai; Jinda Fan; Zhude Tu; Patrick Zerkel; Robert H Mach; Evan D Kharasch
Journal:  Appl Radiat Isot       Date:  2014-06-02       Impact factor: 1.513

6.  Pharmacological Characterization of Low-to-Moderate Affinity Opioid Receptor Agonists and Brain Imaging with 18F-Labeled Derivatives in Rats.

Authors:  Julian Ott; Mona M Spilhaug; Simone Maschauer; Waqas Rafique; Jimmy E Jakobsson; Karoline Hartvig; Harald Hübner; Peter Gmeiner; Olaf Prante; Patrick J Riss
Journal:  J Med Chem       Date:  2020-08-17       Impact factor: 7.446

Review 7.  A Survey of Molecular Imaging of Opioid Receptors.

Authors:  Paul Cumming; János Marton; Tuomas O Lilius; Dag Erlend Olberg; Axel Rominger
Journal:  Molecules       Date:  2019-11-19       Impact factor: 4.411
  7 in total

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