Literature DB >> 24284904

Severe demodexfolliculorum-associated oculocutaneous rosacea in a girl successfully treated with ivermectin.

Megan Brown1, Angela Hernández-Martín2, Ana Clement3, Isabel Colmenero4, Antonio Torrelo2.   

Abstract

IMPORTANCE: There is a limited therapeutic armamentarium for recalcitrant cases of childhood rosacea. OBSERVATIONS: We report the case of a 12-year-old girl who presented with severe ocular and cutaneous rosacea unresponsive to oral doxycycline, oral isotretinoin, and topical tacrolimus. A biopsy specimen showed numerous mites within the folliculosebaceous unit. Treatment with a single dose of oral ivermectin achieved resolution of her symptoms. CONCLUSIONS AND RELEVANCE: The causative role of Demodex folliculorum should be considered in immunocompetent children with rosacea or rosacea-like refractory eruptions. In such cases, treatment with ivermectin can be beneficial.

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Year:  2014        PMID: 24284904     DOI: 10.1001/jamadermatol.2013.7688

Source DB:  PubMed          Journal:  JAMA Dermatol        ISSN: 2168-6068            Impact factor:   10.282


  5 in total

Review 1.  Rosacea: new and emerging treatments.

Authors:  Farah A Moustafa; Laura F Sandoval; Steven R Feldman
Journal:  Drugs       Date:  2014-09       Impact factor: 9.546

Review 2.  [Primary human demodicosis. A disease sui generis].

Authors:  C-K Hsu; A Zink; K-J Wei; E Dzika; G Plewig; W Chen
Journal:  Hautarzt       Date:  2015-03       Impact factor: 0.751

Review 3.  Broadening the range of use cases for ivermectin - a review of the evidence.

Authors:  Christian Kositz; John Bradley; Harry Hutchins; Anna Last; Umberto D'Alessandro; Michael Marks
Journal:  Trans R Soc Trop Med Hyg       Date:  2022-03-02       Impact factor: 2.455

Review 4.  New developments in the treatment of rosacea - role of once-daily ivermectin cream.

Authors:  Leah A Cardwell; Hossein Alinia; Sara Moradi Tuchayi; Steven R Feldman
Journal:  Clin Cosmet Investig Dermatol       Date:  2016-03-18

5.  Rosacea Granulomatosis in a Neutropenic Leukemic Patient.

Authors:  Woo Joo Lee; Natan Kraitman; Carlos J Sarriera-Lazaro; John Greene
Journal:  Cureus       Date:  2022-03-19
  5 in total

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