Literature DB >> 24284316

Palmitoylation and p8-mediated human T-cell leukemia virus type 1 transmission.

Dustin Edwards1, Risaku Fukumoto, Maria Fernanda de Castro-Amarante, Luiz Carlos Junior Alcantara, Bernardo Galvão-Castro, Robyn Washington Parks, Cynthia Pise-Masison, Genoveffa Franchini.   

Abstract

The orf-I gene of human T-cell leukemia type 1 (HTLV-1) encodes p8 and p12 and has a conserved cysteine at position 39. p8 and p12 form disulfide-linked dimers, and only the monomeric forms of p8 and p12 are palmitoylated. Mutation of cysteine 39 to alanine (C39A) abrogated dimerization and palmitoylation of both proteins. However, the ability of p8 to localize to the cell surface and to increase cell adhesion and viral transmission was not affected by the C39A mutation.

Entities:  

Mesh：

Substances：

Year:  2013        PMID： 24284316      PMCID： PMC3911539          DOI： 10.1128/JVI.03444-13

Source DB:  PubMed          Journal:  J Virol        ISSN： 0022-538X            Impact factor:   5.103


  21 in total

1.  HTLV-I associated myelopathy, a new clinical entity.

Authors:  M Osame; K Usuku; S Izumo; N Ijichi; H Amitani; A Igata; M Matsumoto; M Tara
Journal:  Lancet       Date:  1986-05-03       Impact factor: 79.321

2.  HTLV-1 p12(I) protein enhances STAT5 activation and decreases the interleukin-2 requirement for proliferation of primary human peripheral blood mononuclear cells.

Authors:  C Nicot; J C Mulloy; M G Ferrari; J M Johnson; K Fu; R Fukumoto; R Trovato; J Fullen; W J Leonard; G Franchini
Journal:  Blood       Date:  2001-08-01       Impact factor: 22.113

3.  Metabolic labelling of membrane microdomains/rafts in Jurkat cells indicates the presence of glycerophospholipids implicated in signal transduction by the CD3 T-cell receptor.

Authors:  Alexandre K Rouquette-Jazdanian; Claudette Pelassy; Jean-Philippe Breittmayer; Jean-Louis Cousin; Claude Aussel
Journal:  Biochem J       Date:  2002-05-01       Impact factor: 3.857

4.  A conserved calcineurin-binding motif in human T lymphotropic virus type 1 p12I functions to modulate nuclear factor of activated T cell activation.

Authors:  Seung-jae Kim; Wei Ding; Björn Albrecht; Patrick L Green; Michael D Lairmore
Journal:  J Biol Chem       Date:  2003-02-24       Impact factor: 5.157

5.  Human T-cell lymphotropic virus type 1 p12(I) expression increases cytoplasmic calcium to enhance the activation of nuclear factor of activated T cells.

Authors:  Wei Ding; Björn Albrecht; Robert E Kelley; Natarajan Muthusamy; Seung-Jae Kim; Ruth A Altschuld; Michael D Lairmore
Journal:  J Virol       Date:  2002-10       Impact factor: 5.103

6.  Antibodies to human T-lymphotropic virus type-I in patients with tropical spastic paraparesis.

Authors:  A Gessain; F Barin; J C Vernant; O Gout; L Maurs; A Calender; G de Thé
Journal:  Lancet       Date:  1985-08-24       Impact factor: 79.321

7.  Isolation and characterization of retrovirus from cell lines of human adult T-cell leukemia and its implication in the disease.

Authors:  M Yoshida; I Miyoshi; Y Hinuma
Journal:  Proc Natl Acad Sci U S A       Date:  1982-03       Impact factor: 11.205

8.  HTLV-1 associated myelopathy in an HTLV-1 and HBV double carrier family: report of a case and the mode of vertical transmission of both viruses.

Authors:  F Nakamura; H Kajihara; M Nakamura; H Sasaki; T Kumamoto; K Okada
Journal:  J Gastroenterol Hepatol       Date:  1989 Jul-Aug       Impact factor: 4.029

9.  Human adult T-cell leukemia virus: complete nucleotide sequence of the provirus genome integrated in leukemia cell DNA.

Authors:  M Seiki; S Hattori; Y Hirayama; M Yoshida
Journal:  Proc Natl Acad Sci U S A       Date:  1983-06       Impact factor: 11.205

10.  Detection and isolation of type C retrovirus particles from fresh and cultured lymphocytes of a patient with cutaneous T-cell lymphoma.

Authors:  B J Poiesz; F W Ruscetti; A F Gazdar; P A Bunn; J D Minna; R C Gallo
Journal:  Proc Natl Acad Sci U S A       Date:  1980-12       Impact factor: 11.205
View more
  6 in total

1.  First report of HTLV-1 truncated p12 protein in Brazil.

Authors:  Carolina Rosadas; Ana C P Vicente; Louise Zanella; Mauro J Cabral-Castro; José M Peralta; Marzia Puccioni-Sohler
Journal:  Virulence       Date:  2016-12-14       Impact factor: 5.882

2.  Co-dependence of HTLV-1 p12 and p8 functions in virus persistence.

Authors:  Cynthia A Pise-Masison; Maria Fernanda de Castro-Amarante; Yoshimi Enose-Akahata; R Cody Buchmann; Claudio Fenizia; Robyn Washington Parks; Dustin Edwards; Martina Fiocchi; Luiz Carlos Alcantara; Izabela Bialuk; Jhanelle Graham; Jean-Claude Walser; Katherine McKinnon; Bernardo Galvão-Castro; Antoine Gessain; David Venzon; Steven Jacobson; Genoveffa Franchini
Journal:  PLoS Pathog       Date:  2014-11-06       Impact factor: 6.823

Review 3.  Molecular Mechanisms of HTLV-1 Cell-to-Cell Transmission.

Authors:  Christine Gross; Andrea K Thoma-Kress
Journal:  Viruses       Date:  2016-03-09       Impact factor: 5.048

4.  Quantitating the Transfer of the HTLV-1 p8 Protein Between T-Cells by Flow Cytometry.

Authors:  Norbert Donhauser; Stefanie Heym; Andrea K Thoma-Kress
Journal:  Front Microbiol       Date:  2018-03-07       Impact factor: 5.640

Review 5.  Non-Structural Proteins from Human T-cell Leukemia Virus Type 1 in Cellular Membranes-Mechanisms for Viral Survivability and Proliferation.

Authors:  Elka R Georgieva
Journal:  Int J Mol Sci       Date:  2018-11-08       Impact factor: 5.923

Review 6.  Role of HTLV-1 orf-I encoded proteins in viral transmission and persistence.

Authors:  Sarkis Sarkis; Veronica Galli; Ramona Moles; David Yurick; Georges Khoury; Damian F J Purcell; Genoveffa Franchini; Cynthia A Pise-Masison
Journal:  Retrovirology       Date:  2019-12-18       Impact factor: 4.602
  6 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.