BACKGROUND: Clostridium ramosum is a common enteric anaerobe but infrequently also a cause of pathologic infection. METHODS: Case report and literature review. RESULTS: We reviewed 12 case reports describing infection with C. ramosum. When pathogenic, C. ramosum is cultured most commonly from the inner ear, anaerobic blood samples, or abscesses. Patients with such infections fall into two demographic groups, consisting of young children with ear infections or immunocompromised adults with bacteremia. Resistance of C. ramosum to antibiotics is uncommon. CONCLUSION: Clostridium ramosum is a common but generally commensal bacterial species. Rarely, it becomes pathogenic in young children or immunosuppressed adults.
BACKGROUND:Clostridium ramosum is a common enteric anaerobe but infrequently also a cause of pathologic infection. METHODS: Case report and literature review. RESULTS: We reviewed 12 case reports describing infection with C. ramosum. When pathogenic, C. ramosum is cultured most commonly from the inner ear, anaerobic blood samples, or abscesses. Patients with such infections fall into two demographic groups, consisting of young children with ear infections or immunocompromised adults with bacteremia. Resistance of C. ramosum to antibiotics is uncommon. CONCLUSION:Clostridium ramosum is a common but generally commensal bacterial species. Rarely, it becomes pathogenic in young children or immunosuppressed adults.
Authors: Tao Zuo; Fen Zhang; Grace C Y Lui; Yun Kit Yeoh; Amy Y L Li; Hui Zhan; Yating Wan; Arthur C K Chung; Chun Pan Cheung; Nan Chen; Christopher K C Lai; Zigui Chen; Eugene Y K Tso; Kitty S C Fung; Veronica Chan; Lowell Ling; Gavin Joynt; David S C Hui; Francis K L Chan; Paul K S Chan; Siew C Ng Journal: Gastroenterology Date: 2020-05-20 Impact factor: 33.883