Literature DB >> 24283747

Selected gastrointestinal cancer presentations from the American Society of Clinical Oncology annual meeting 2013 in review: it is not about the destination, it is about the journey.

Mario Scartozzi1, Riccardo Giampieri, Michela Del Prete, Luca Faloppi, Maristella Bianconi, Bruno Vincenzi, Giuseppe Tonini, Daniele Santini, Stefano Cascinu.   

Abstract

INTRODUCTION: In the GI tumors area, key findings from the American Society of Clinical Oncology 2013 annual meeting were long awaited, particularly in colorectal, gastric and pancreatic cancer. AREAS COVERED: The following pages briefly present and comment on a selection of those studies considered most relevant for clinical practice and future research planning. The following trials were then reviewed: the FIRE-3, Triplet + beva (TRIBE), new EPOC, CAIRO-3 and SAKK in colorectal cancer, the TRIO-013/LOGIC and COUGAR-02 in gastric cancer and the metastatic adenocarcinoma of the pancreas (MPACT) and LAP07 in pancreatic cancer. EXPERT OPINION: Although the proportion of clinical questions that these trials were able to answer was almost exactly paralleled by the introduction of new questions to be responded in the next (hopefully) few years, globally they represented a significant improvement in our knowledge about colorectal cancer and pancreatic tumors.

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Year:  2013        PMID: 24283747     DOI: 10.1517/14656566.2014.860964

Source DB:  PubMed          Journal:  Expert Opin Pharmacother        ISSN: 1465-6566            Impact factor:   3.889


  5 in total

1.  miR-503 inhibits cell proliferation and induces apoptosis in colorectal cancer cells by targeting E2F3.

Authors:  Shun-Wu Chang; Jie Yue; Bao-Chun Wang; Xue-Li Zhang
Journal:  Int J Clin Exp Pathol       Date:  2015-10-01

2.  Impact of tapering and discontinuation of bevacizumab in patients with progressive glioblastoma.

Authors:  Anne Hertenstein; Thomas Hielscher; Oliver Menn; Benedikt Wiestler; Frank Winkler; Michael Platten; Wolfgang Wick; Antje Wick
Journal:  J Neurooncol       Date:  2016-07-15       Impact factor: 4.130

Review 3.  MicroRNAs as novel predictive biomarkers and therapeutic targets in colorectal cancer.

Authors:  Verena Stiegelbauer; Samantha Perakis; Alexander Deutsch; Hui Ling; Armin Gerger; Martin Pichler
Journal:  World J Gastroenterol       Date:  2014-09-07       Impact factor: 5.742

Review 4.  Basics and Frontiers on Pancreatic Cancer for Radiation Oncology: Target Delineation, SBRT, SIB technique, MRgRT, Particle Therapy, Immunotherapy and Clinical Guidelines.

Authors:  Francesco Cellini; Alessandra Arcelli; Nicola Simoni; Luciana Caravatta; Milly Buwenge; Angela Calabrese; Oronzo Brunetti; Domenico Genovesi; Renzo Mazzarotto; Francesco Deodato; Gian Carlo Mattiucci; Nicola Silvestris; Vincenzo Valentini; Alessio Giuseppe Morganti
Journal:  Cancers (Basel)       Date:  2020-06-29       Impact factor: 6.639

5.  TNFRSF10C methylation is a new epigenetic biomarker for colorectal cancer.

Authors:  Cong Zhou; Ranran Pan; Haochang Hu; Bin Li; Jie Dai; Xiuru Ying; Hang Yu; Jie Zhong; Yiyi Mao; Yihan Zhang; Dongping Wu; Shiwei Duan
Journal:  PeerJ       Date:  2018-09-13       Impact factor: 2.984

  5 in total

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