OBJECTIVES: Pain is the cardinal feature in fibromyalgia syndrome (FM) and increases the risk of anxiety and depression. Patients with FM frequently report sleep disturbances as well. Sleep may mediate the association between pain and emotional symptoms, an idea which has been scarcely studied. The objective of this study was to uncover the role of subjective and objective sleep characteristics as mediators of the relationship between pain and anxiety and depression in FM. MATERIALS AND METHODS: Fifty-five female with FM (mean age, 47.62 ± 7.64 y) were assessed to obtain self-reported measures of pain, sleep quality, anxiety and depression levels, and self-efficacy to cope with pain. An ambulatory polysomnographic recording was performed to assess sleep architecture. RESULTS: Subjective poor sleep quality was found in all participtants. Pain correlated with subjective and objective sleep parameters, self-efficacy, anxiety, and, marginally, with depression. The mediated regression analysis suggested that the best models to explain the impact of pain on anxiety and depression included, as mediators, subjective sleep quality, objective sleep efficiency, and self-efficacy (these models explained 34% of the variance), with objective sleep efficiency being the mediator with the highest influence (P<0.05). DISCUSSION: These findings show a high prevalence of sleep problems in individuals with FM and suggest that they play a role in the relationship between pain and anxiety and depression. In fact, the impact of chronic pain on the later emotional variables was mediated not only by self-efficacy but also by subjective sleep quality and, especially, by objective sleep efficiency.
OBJECTIVES:Pain is the cardinal feature in fibromyalgia syndrome (FM) and increases the risk of anxiety and depression. Patients with FM frequently report sleep disturbances as well. Sleep may mediate the association between pain and emotional symptoms, an idea which has been scarcely studied. The objective of this study was to uncover the role of subjective and objective sleep characteristics as mediators of the relationship between pain and anxiety and depression in FM. MATERIALS AND METHODS: Fifty-five female with FM (mean age, 47.62 ± 7.64 y) were assessed to obtain self-reported measures of pain, sleep quality, anxiety and depression levels, and self-efficacy to cope with pain. An ambulatory polysomnographic recording was performed to assess sleep architecture. RESULTS: Subjective poor sleep quality was found in all participtants. Pain correlated with subjective and objective sleep parameters, self-efficacy, anxiety, and, marginally, with depression. The mediated regression analysis suggested that the best models to explain the impact of pain on anxiety and depression included, as mediators, subjective sleep quality, objective sleep efficiency, and self-efficacy (these models explained 34% of the variance), with objective sleep efficiency being the mediator with the highest influence (P<0.05). DISCUSSION: These findings show a high prevalence of sleep problems in individuals with FM and suggest that they play a role in the relationship between pain and anxiety and depression. In fact, the impact of chronic pain on the later emotional variables was mediated not only by self-efficacy but also by subjective sleep quality and, especially, by objective sleep efficiency.
Authors: Daniel G Whitney; Sarah Bell; Daniel Whibley; Wilma M A Van der Slot; Edward A Hurvitz; Heidi J Haapala; Mark D Peterson; Seth A Warschausky Journal: Dev Med Child Neurol Date: 2020-05-10 Impact factor: 5.449
Authors: Shari S Rogal; Klaus Bielefeldt; Ajay D Wasan; Eva Szigethy; Francis Lotrich; Andrea F DiMartini Journal: Dig Dis Sci Date: 2014-11-30 Impact factor: 3.199
Authors: Daniel G Whitney; Seth A Warschausky; Daniel Whibley; Anna Kratz; Susan L Murphy; Edward A Hurvitz; Mark D Peterson Journal: Neurol Clin Pract Date: 2020-06
Authors: Laura Torrecillas-Martínez; Andrés Catena; Francisco O'Valle; Miguel Padial-Molina; Pablo Galindo-Moreno Journal: Int J Clin Health Psychol Date: 2019-03-04