Literature DB >> 24276040

Prognostic significance of being overweight and obese at diagnosis in children with acute lymphoblastic leukemia.

Fahad K Aldhafiri1, John H McColl, John J Reilly.   

Abstract

This study tested the hypothesis that being overweight/obese at diagnosis of childhood ALL was related to risk of relapse. In a national cohort of 1033 patients from the UK, there was no evidence that weight status at diagnosis was related significantly to risk of relapse: log-rank test (P=0.90) with overweight and obesity as the exposure (n=917); individual (P=0.42) and stepwise (P=0.96) proportional hazards models, with BMI Z score as the exposure. The study does not support the hypothesis that being overweight/obese at diagnosis impairs prognosis in childhood ALL in the UK.

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Year:  2014        PMID： 24276040     DOI： 10.1097/MPH.0000000000000056

Source DB:  PubMed          Journal:  J Pediatr Hematol Oncol        ISSN： 1077-4114            Impact factor:   1.289


  9 in total

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