Literature DB >> 24275884

Small cell tumors of the thyroid gland: a review.

Catarina Eloy1, José Manuel Cameselle-Teijeiro, Emmanuel Rousseau, Manuel Sobrinho-Simões.   

Abstract

The small cell group of thyroid tumors that includes lymphoma, poorly differentiated carcinoma, medullary carcinoma, secondary neoplasms, as well as tumors with uncertain histogenesis, remains as a valid diagnostic cul-de-sac due to its heterogeneous constitution. The existence of small cell thyroid tumors with EWSR1-FLI1 rearrangement together with neuroendocrine and/or carcinomatous differentiation raises not only differential diagnostic problems but also a very interesting therapeutic dilemma. This review explores the classification of small cell tumors of the thyroid taking into account the immunophenotype and molecular profile of such tumors.

Entities:  

Keywords:  calcitonin; medullary carcinoma; neuroendocrine tumor; primary extraskeletal Ewing family tumors; small cell carcinoma; thyroid

Mesh:

Year:  2013        PMID: 24275884     DOI: 10.1177/1066896913510029

Source DB:  PubMed          Journal:  Int J Surg Pathol        ISSN: 1066-8969            Impact factor:   1.271


  6 in total

1.  Carcinomas of the Thyroid with Ewing Family Tumor Elements (CEFTEs): A Diagnostic Challenge Before Surgery.

Authors:  Silvia Taccogna; Rinaldo Guglielmi; Agnese Persichetti; Carmelo Morano; Francesco Angelini; Sara Ienzi; Stefania Scarpino; Andrea Liverani; Alessio Annovazzi; Enrico Papini
Journal:  Head Neck Pathol       Date:  2020-02-19

2.  EWSR1 rearrangement is a frequent event in papillary thyroid carcinoma and in carcinoma of the thyroid with Ewing family tumor elements (CEFTE).

Authors:  G Oliveira; A Polónia; J M Cameselle-Teijeiro; D Leitão; S Sapia; M Sobrinho-Simões; C Eloy
Journal:  Virchows Arch       Date:  2017-02-24       Impact factor: 4.064

Review 3.  Multilayered heterogeneity as an intrinsic hallmark of neuroendocrine tumors.

Authors:  Sergio Pedraza-Arévalo; Manuel D Gahete; Emilia Alors-Pérez; Raúl M Luque; Justo P Castaño
Journal:  Rev Endocr Metab Disord       Date:  2018-06       Impact factor: 6.514

4.  Contribution of cytologic examination to diagnosis of poorly differentiated thyroid carcinoma.

Authors:  Na Rae Kim; Jae Yeon Seok; Yoo Seung Chung; Joon Hyop Lee; Dong Hae Chung
Journal:  J Pathol Transl Med       Date:  2020-02-05

Review 5.  Thyroid metastasis from small cell lung carcinoma: a case report and review of the literature.

Authors:  Ahmet Selçuk Can; Gülistan Köksal
Journal:  J Med Case Rep       Date:  2015-10-07

6.  EWSR1 rearrangement in papillary thyroid microcarcinoma is related to classic morphology and the presence of small-cell phenotype.

Authors:  Bozidar Kovacevic; Ana Caramelo; Vesna Skuletic; Snezana Cerovic; Catarina Eloy
Journal:  Bosn J Basic Med Sci       Date:  2022-02-01       Impact factor: 3.363

  6 in total

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