| Literature DB >> 24275884 |
Catarina Eloy1, José Manuel Cameselle-Teijeiro, Emmanuel Rousseau, Manuel Sobrinho-Simões.
Abstract
The small cell group of thyroid tumors that includes lymphoma, poorly differentiated carcinoma, medullary carcinoma, secondary neoplasms, as well as tumors with uncertain histogenesis, remains as a valid diagnostic cul-de-sac due to its heterogeneous constitution. The existence of small cell thyroid tumors with EWSR1-FLI1 rearrangement together with neuroendocrine and/or carcinomatous differentiation raises not only differential diagnostic problems but also a very interesting therapeutic dilemma. This review explores the classification of small cell tumors of the thyroid taking into account the immunophenotype and molecular profile of such tumors.Entities:
Keywords: calcitonin; medullary carcinoma; neuroendocrine tumor; primary extraskeletal Ewing family tumors; small cell carcinoma; thyroid
Mesh:
Year: 2013 PMID: 24275884 DOI: 10.1177/1066896913510029
Source DB: PubMed Journal: Int J Surg Pathol ISSN: 1066-8969 Impact factor: 1.271