Christos Komninos1, Tae Young Shin2, Patrick Tuliao3, Young Eun Yoon3, Kyo Chul Koo3, Chien-Hsiang Chang3, Sang Woon Kim3, Ji Yong Ha3, Woong Kyu Han3, Koon Ho Rha4. 1. Department of Urology and Urological Science Institute, Yonsei University College of Medicine, Seoul, South Korea; Department of Urology, General Hospital of Nikaia 'St. Panteleimon', Athens, Greece. 2. Department of Urology, Chuncheon Sacred Hospital, Hallym Medical College, Chuncheon, South Korea. 3. Department of Urology and Urological Science Institute, Yonsei University College of Medicine, Seoul, South Korea. 4. Department of Urology and Urological Science Institute, Yonsei University College of Medicine, Seoul, South Korea. Electronic address: khrha@yuhs.ac.
Abstract
BACKGROUND: Trifecta achievement in partial nephrectomy (PN) is defined as the combination of warm ischemia time ≤ 20 min, negative surgical margins, and no surgical complications. OBJECTIVE: To compare trifecta achievement between robotic, laparoendoscopic, single-site (R-LESS) PN and multiport robotic PN (RPN). DESIGN, SETTING, AND PARTICIPANTS: Data from 167 patients who underwent RPN from 2006 to 2012 were retrospectively analyzed. OUTCOME MEASUREMENTS AND STATISTICAL ANALYSIS: Primary outcome measurement was trifecta achievement; secondary outcome was the perioperative and postoperative comparison between groups. The measurements were estimated and analyzed with SPSS v.18 using univariable, multivariable, and subgroup analyses. RESULTS AND LIMITATIONS: Eighty-nine patients were treated with RPN and 78 were treated with R-LESS PN. Baseline characteristics of both groups were similar. Trifecta was achieved in 38 patients (42.7%) in the multiport RPN group and 20 patients (25.6%) in the R-LESS PN group (p=0.021). Patients in the R-LESS PN group had longer mean operative time, warm ischemia time, and increased estimated glomerular filtration rate (eGFR) percentage change. No significant differences were found between the two groups in days of hospitalization, blood loss, postoperative eGFR, positive surgical margins, and surgical complications. Patients with increased PADUA and RENAL scores, infiltration of the collecting system, and renal sinus involvement had an increased probability of not achieving the trifecta. In regression analysis, the type of procedure and the tumor size could predict trifecta accomplishment (p=0.019 and 0.043, respectively). The retrospective study, the low number of series, and the controversial definition of trifecta were the main limitations. CONCLUSIONS: The trifecta was achieved in significantly more patients who underwent multiport RPN than those who underwent R-LESS PN. R-LESS PN could be an alternative option for patients with decreased tumor size, low PADUA and RENAL scores, and without renal sinus or collecting system involvement. PATIENT SUMMARY: In this study, we looked at the outcomes of patients who had undergone robotic partial nephrectomy. We found that conventional robotic partial nephrectomy is superior to R-LESS partial nephrectomy with regard to the accomplishment of negative margins, reduced warm ischemia time, and minimal surgical complications.
BACKGROUND: Trifecta achievement in partial nephrectomy (PN) is defined as the combination of warm ischemia time ≤ 20 min, negative surgical margins, and no surgical complications. OBJECTIVE: To compare trifecta achievement between robotic, laparoendoscopic, single-site (R-LESS) PN and multiport robotic PN (RPN). DESIGN, SETTING, AND PARTICIPANTS: Data from 167 patients who underwent RPN from 2006 to 2012 were retrospectively analyzed. OUTCOME MEASUREMENTS AND STATISTICAL ANALYSIS: Primary outcome measurement was trifecta achievement; secondary outcome was the perioperative and postoperative comparison between groups. The measurements were estimated and analyzed with SPSS v.18 using univariable, multivariable, and subgroup analyses. RESULTS AND LIMITATIONS: Eighty-nine patients were treated with RPN and 78 were treated with R-LESS PN. Baseline characteristics of both groups were similar. Trifecta was achieved in 38 patients (42.7%) in the multiport RPN group and 20 patients (25.6%) in the R-LESS PN group (p=0.021). Patients in the R-LESS PN group had longer mean operative time, warm ischemia time, and increased estimated glomerular filtration rate (eGFR) percentage change. No significant differences were found between the two groups in days of hospitalization, blood loss, postoperative eGFR, positive surgical margins, and surgical complications. Patients with increased PADUA and RENAL scores, infiltration of the collecting system, and renal sinus involvement had an increased probability of not achieving the trifecta. In regression analysis, the type of procedure and the tumor size could predict trifecta accomplishment (p=0.019 and 0.043, respectively). The retrospective study, the low number of series, and the controversial definition of trifecta were the main limitations. CONCLUSIONS: The trifecta was achieved in significantly more patients who underwent multiport RPN than those who underwent R-LESS PN. R-LESS PN could be an alternative option for patients with decreased tumor size, low PADUA and RENAL scores, and without renal sinus or collecting system involvement. PATIENT SUMMARY: In this study, we looked at the outcomes of patients who had undergone robotic partial nephrectomy. We found that conventional robotic partial nephrectomy is superior to R-LESS partial nephrectomy with regard to the accomplishment of negative margins, reduced warm ischemia time, and minimal surgical complications.
Authors: Steffen Lebentrau; Sven Rauter; Daniel Baumunk; Frank Christoph; Frank König; Matthias May; Martin Schostak Journal: World J Urol Date: 2016-08-12 Impact factor: 4.226
Authors: Dae Keun Kim; Lawrence H C Kim; Ali Abdel Raheem; Tae Young Shin; Ibrahim Alabdulaali; Young Eun Yoon; Woong Kyu Han; Koon Ho Rha Journal: PLoS One Date: 2016-03-17 Impact factor: 3.240
Authors: Joseph D Shirk; David D Thiel; Eric M Wallen; Jennifer M Linehan; Wesley M White; Ketan K Badani; James R Porter Journal: JAMA Netw Open Date: 2019-09-04