Literature DB >> 24274256

Metal-free, acid-promoted synthesis of imidazole derivatives via a multicomponent reaction.

Chung-Yu Chen1, Wan-Ping Hu, Pi-Cheng Yan, Gopal Chandru Senadi, Jeh-Jeng Wang.   

Abstract

An expedient and metal-free synthetic route has been developed for the construction of tri- and tetrasubstituted imidazole derivatives via acid promoted multicomponent reaction methodology. The reaction proceeded smoothly with a range of functionalities to produce the imidazole scaffolds in good to excellent yields.

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Year:  2013        PMID： 24274256     DOI： 10.1021/ol402892z

Source DB:  PubMed          Journal:  Org Lett        ISSN： 1523-7052            Impact factor:   6.005


  7 in total

Review 1.  Current advances in the synthesis and biological potencies of tri- and tetra-substituted 1H-imidazoles.

Authors:  Majid M Heravi; Mansoureh Daraie; Vahideh Zadsirjan
Journal:  Mol Divers       Date:  2015-04-12       Impact factor: 2.943

Review 2.  Transition metal-free one-pot synthesis of nitrogen-containing heterocycles.

Authors:  Simpal Kumari; Dharma Kishore; Sarvesh Paliwal; Rajani Chauhan; Jaya Dwivedi; Aakanksha Mishra
Journal:  Mol Divers       Date:  2015-06-09       Impact factor: 2.943

3.  Mechanistic Pathways in Amide Activation: Flexible Synthesis of Oxazoles and Imidazoles.

Authors:  Giovanni Di Mauro; Boris Maryasin; Daniel Kaiser; Saad Shaaban; Leticia González; Nuno Maulide
Journal:  Org Lett       Date:  2017-07-13       Impact factor: 6.005

4.  A palladium-catalyzed synthesis of (hetero)aryl-substituted imidazoles from aryl halides, imines and carbon monoxide.

Authors:  Jevgenijs Tjutrins; Bruce A Arndtsen
Journal:  Chem Sci       Date:  2016-11-03       Impact factor: 9.825

5.  Polysubstituted Imidazoles as LysoTracker Molecules: Their Synthesis via Iodine/H2O and Cell-Imaging Studies.

Authors:  Saswati Adhikary; Leena Majumder; Sourav Pakrashy; Ravuri Srinath; Kaustuv Mukherjee; Chitra Mandal; Biswadip Banerji
Journal:  ACS Omega       Date:  2020-06-11

6.  Convenient one-pot synthesis of 1,2,4-oxadiazoles and 2,4,6-triarylpyridines using graphene oxide (GO) as a metal-free catalyst: importance of dual catalytic activity.

Authors:  Puja Basak; Sourav Dey; Pranab Ghosh
Journal:  RSC Adv       Date:  2021-09-28       Impact factor: 4.036

7.  Base-Promoted Annulation of Amidoximes with Alkynes: Simple Access to 2,4-Disubstituted Imidazoles.

Authors:  Hina Mehmood; Muhammad Asif Iqbal; Le Lu; Ruimao Hua
Journal:  Molecules       Date:  2020-08-09       Impact factor: 4.411
  7 in total

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