Literature DB >> 24273241

Pathway Commons at virtual cell: use of pathway data for mathematical modeling.

Michael L Blinov1, James C Schaff, Oliver Ruebenacker, Xintao Wei, Dan Vasilescu, Fei Gao, Frank Morgan, Li Ye, Anuradha Lakshminarayana, Ion I Moraru, Leslie M Loew.   

Abstract

UNLABELLED: Pathway Commons is a resource permitting simultaneous queries of multiple pathway databases. However, there is no standard mechanism for using these data (stored in BioPAX format) to annotate and build quantitative mathematical models. Therefore, we developed a new module within the virtual cell modeling and simulation software. It provides pathway data retrieval and visualization and enables automatic creation of executable network models directly from qualitative connections between pathway nodes.
AVAILABILITY AND IMPLEMENTATION: Available at Virtual Cell (http://vcell.org/). Application runs on all major platforms and does not require registration for use on the user’s computer. Tutorials and video are available at user guide page.

Mesh:

Year:  2013        PMID: 24273241      PMCID: PMC3892693          DOI: 10.1093/bioinformatics/btt660

Source DB:  PubMed          Journal:  Bioinformatics        ISSN: 1367-4803            Impact factor:   6.937


  9 in total

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Authors:  M Hucka; A Finney; H M Sauro; H Bolouri; J C Doyle; H Kitano; A P Arkin; B J Bornstein; D Bray; A Cornish-Bowden; A A Cuellar; S Dronov; E D Gilles; M Ginkel; V Gor; I I Goryanin; W J Hedley; T C Hodgman; J-H Hofmeyr; P J Hunter; N S Juty; J L Kasberger; A Kremling; U Kummer; N Le Novère; L M Loew; D Lucio; P Mendes; E Minch; E D Mjolsness; Y Nakayama; M R Nelson; P F Nielsen; T Sakurada; J C Schaff; B E Shapiro; T S Shimizu; H D Spence; J Stelling; K Takahashi; M Tomita; J Wagner; J Wang
Journal:  Bioinformatics       Date:  2003-03-01       Impact factor: 6.937

Review 2.  Using views of Systems Biology Cloud: application for model building.

Authors:  Oliver Ruebenacker; Michael Blinov
Journal:  Theory Biosci       Date:  2010-08-21       Impact factor: 1.919

3.  Minimum information requested in the annotation of biochemical models (MIRIAM).

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Journal:  Nat Biotechnol       Date:  2005-12       Impact factor: 54.908

4.  Integrating BioPAX pathway knowledge with SBML models.

Authors:  O Ruebenacker; I I Moraru; J C Schaff; M L Blinov
Journal:  IET Syst Biol       Date:  2009-09       Impact factor: 1.615

5.  Spatial modeling of cell signaling networks.

Authors:  Ann E Cowan; Ion I Moraru; James C Schaff; Boris M Slepchenko; Leslie M Loew
Journal:  Methods Cell Biol       Date:  2012       Impact factor: 1.441

6.  Virtual Cell modelling and simulation software environment.

Authors:  I I Moraru; J C Schaff; B M Slepchenko; M L Blinov; F Morgan; A Lakshminarayana; F Gao; Y Li; L M Loew
Journal:  IET Syst Biol       Date:  2008-09       Impact factor: 1.615

7.  Pathway Commons, a web resource for biological pathway data.

Authors:  Ethan G Cerami; Benjamin E Gross; Emek Demir; Igor Rodchenkov; Ozgün Babur; Nadia Anwar; Nikolaus Schultz; Gary D Bader; Chris Sander
Journal:  Nucleic Acids Res       Date:  2010-11-10       Impact factor: 16.971

8.  The BioPAX community standard for pathway data sharing.

Authors:  Emek Demir; Michael P Cary; Suzanne Paley; Ken Fukuda; Christian Lemer; Imre Vastrik; Guanming Wu; Peter D'Eustachio; Carl Schaefer; Joanne Luciano; Frank Schacherer; Irma Martinez-Flores; Zhenjun Hu; Veronica Jimenez-Jacinto; Geeta Joshi-Tope; Kumaran Kandasamy; Alejandra C Lopez-Fuentes; Huaiyu Mi; Elgar Pichler; Igor Rodchenkov; Andrea Splendiani; Sasha Tkachev; Jeremy Zucker; Gopal Gopinath; Harsha Rajasimha; Ranjani Ramakrishnan; Imran Shah; Mustafa Syed; Nadia Anwar; Ozgün Babur; Michael Blinov; Erik Brauner; Dan Corwin; Sylva Donaldson; Frank Gibbons; Robert Goldberg; Peter Hornbeck; Augustin Luna; Peter Murray-Rust; Eric Neumann; Oliver Ruebenacker; Oliver Reubenacker; Matthias Samwald; Martijn van Iersel; Sarala Wimalaratne; Keith Allen; Burk Braun; Michelle Whirl-Carrillo; Kei-Hoi Cheung; Kam Dahlquist; Andrew Finney; Marc Gillespie; Elizabeth Glass; Li Gong; Robin Haw; Michael Honig; Olivier Hubaut; David Kane; Shiva Krupa; Martina Kutmon; Julie Leonard; Debbie Marks; David Merberg; Victoria Petri; Alex Pico; Dean Ravenscroft; Liya Ren; Nigam Shah; Margot Sunshine; Rebecca Tang; Ryan Whaley; Stan Letovksy; Kenneth H Buetow; Andrey Rzhetsky; Vincent Schachter; Bruno S Sobral; Ugur Dogrusoz; Shannon McWeeney; Mirit Aladjem; Ewan Birney; Julio Collado-Vides; Susumu Goto; Michael Hucka; Nicolas Le Novère; Natalia Maltsev; Akhilesh Pandey; Paul Thomas; Edgar Wingender; Peter D Karp; Chris Sander; Gary D Bader
Journal:  Nat Biotechnol       Date:  2010-09-09       Impact factor: 54.908

9.  BioModels Database: a free, centralized database of curated, published, quantitative kinetic models of biochemical and cellular systems.

Authors:  Nicolas Le Novère; Benjamin Bornstein; Alexander Broicher; Mélanie Courtot; Marco Donizelli; Harish Dharuri; Lu Li; Herbert Sauro; Maria Schilstra; Bruce Shapiro; Jacky L Snoep; Michael Hucka
Journal:  Nucleic Acids Res       Date:  2006-01-01       Impact factor: 16.971

  9 in total
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2.  Critical Genomic Networks and Vasoreactive Variants in Idiopathic Pulmonary Arterial Hypertension.

Authors:  Anna R Hemnes; Min Zhao; James West; John H Newman; Stuart Rich; Stephen L Archer; Ivan M Robbins; Timothy S Blackwell; Joy Cogan; James E Loyd; Zhongming Zhao; Christa Gaskill; Christopher Jetter; Jonathan A Kropski; Susan M Majka; Eric D Austin
Journal:  Am J Respir Crit Care Med       Date:  2016-08-15       Impact factor: 21.405

3.  Large-scale automated machine reading discovers new cancer-driving mechanisms.

Authors:  Marco A Valenzuela-Escárcega; Özgün Babur; Gus Hahn-Powell; Dane Bell; Thomas Hicks; Enrique Noriega-Atala; Xia Wang; Mihai Surdeanu; Emek Demir; Clayton T Morrison
Journal:  Database (Oxford)       Date:  2018-01-01       Impact factor: 3.451

4.  Constructing a molecular interaction network for thyroid cancer via large-scale text mining of gene and pathway events.

Authors:  Chengkun Wu; Jean-Marc Schwartz; Georg Brabant; Shao-Liang Peng; Goran Nenadic
Journal:  BMC Syst Biol       Date:  2015-12-09

Review 5.  DBHR: a collection of databases relevant to human research.

Authors:  Shahid Ullah; Wajeeha Rahman; Farhan Ullah; Gulzar Ahmad; Muhmmad Ijaz; Tianshun Gao
Journal:  Future Sci OA       Date:  2021-01-20

6.  GCGene: a gene resource for gastric cancer with literature evidence.

Authors:  Min Zhao; Luming Chen; Yining Liu; Hong Qu
Journal:  Oncotarget       Date:  2016-06-07
  6 in total

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