OBJECTIVE: The effect of acute retrograde gastric electrical stimulation (RGES) on food intake, gastric accommodation, and gastric emptying in obese patients was investigated. METHODS: Simple obesity patients underwent RGES or sham stimulation. The maximum food intake volume was determined and the total calorie of consumed food was calculated. Gastric emptying was determined by (99m) -diethylenetriaminepentaacetic acid scintigraphy. RESULTS: Sixteen obese patients were studied, with a median BMI of 32.1 (IQR, 31.2, 33.8) kg/m(2) . The median gastric emptying time was 106.1 (IQR, 81.8, 122.4) min with sham stimulation and 113.0 (IQR, 83.7, 124.8) min with RGES (P = 0.352). The mean maximum satiety food intake was 580 (IQR, 510, 725) mL with sham stimulation and 490 (IQR, 385, 590) mL with RGES (P = 0.003). No statistically significant difference was noted between sham stimulation and RGES in the 1 and 2-h food retention rate. The total calories of maximum satiety food intake with sham stimulation were 985.2 (IQR, 842.5, 1063.1) kcal and 759.9 (IQR, 547.9, 784.9) kcal with RGES (P = 0.007). CONCLUSIONS: Acute RGES reduces calorie intake by decreasing gastric accommodation in obese subjects.
OBJECTIVE: The effect of acute retrograde gastric electrical stimulation (RGES) on food intake, gastric accommodation, and gastric emptying in obesepatients was investigated. METHODS: Simple obesitypatients underwent RGES or sham stimulation. The maximum food intake volume was determined and the total calorie of consumed food was calculated. Gastric emptying was determined by (99m) -diethylenetriaminepentaacetic acid scintigraphy. RESULTS: Sixteen obesepatients were studied, with a median BMI of 32.1 (IQR, 31.2, 33.8) kg/m(2) . The median gastric emptying time was 106.1 (IQR, 81.8, 122.4) min with sham stimulation and 113.0 (IQR, 83.7, 124.8) min with RGES (P = 0.352). The mean maximum satiety food intake was 580 (IQR, 510, 725) mL with sham stimulation and 490 (IQR, 385, 590) mL with RGES (P = 0.003). No statistically significant difference was noted between sham stimulation and RGES in the 1 and 2-h food retention rate. The total calories of maximum satiety food intake with sham stimulation were 985.2 (IQR, 842.5, 1063.1) kcal and 759.9 (IQR, 547.9, 784.9) kcal with RGES (P = 0.007). CONCLUSIONS: Acute RGES reduces calorie intake by decreasing gastric accommodation in obese subjects.
Authors: Melanie Y Denzer-Lippmann; Stephan Bachlechner; Jan Wielopolski; Marie Fischer; Andrea Buettner; Arndt Doerfler; Christof Schöfl; Gerald Münch; Johannes Kornhuber; Norbert Thürauf Journal: Front Psychol Date: 2017-06-28
Authors: Jan Král; Evžen Machytka; Veronika Horká; Jana Selucká; Filip Doleček; Julius Špičák; Viktorie Kovářová; Martin Haluzík; Marek Bužga Journal: Nutrients Date: 2021-11-26 Impact factor: 5.717