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Literature DB >> 24272834

Prostaglandins and central serotonergic activity in the rat.

Abstract

Pharmacological and biochemical studies indicate that prostaglandins (PGs) exert a modulatory influence on rat brain serotonergic activity. With several experimental approaches, it has been shown that PGEs and PGD2 facilitate central serotonergic activity in rats. On the contrary, PGF2α not only inhibits rat brain serotonergic activity but also antagonizes the facilitatory effect of the other PGs. The studies support the proposed neuromodulatory role for PGs in central synaptic transmission.

Entities: Chemical Species

Year: 1985 PMID： 24272834 DOI： 10.1023/A:1016300424955

Source DB: PubMed Journal: Pharm Res ISSN： 0724-8741 Impact factor: 4.200

43 in total

Review 1. Basic mechanisms of prostaglandin action on autonomic neurotransmission.

Authors: P Hedqvist
Journal: Annu Rev Pharmacol Toxicol Date: 1977 Impact factor: 13.820

2. Stress by restraining potentiates morphine catalepsy in rats.

Authors: S K Bhattacharya; S S Parmar
Journal: Experientia Date: 1985-12-15

Review 3. Prostaglandins and the central nervous system.

Authors: F Coceani
Journal: Arch Intern Med Date: 1974-01

4. Cannabis-induced catalepsy in mice: role of putative neurotransmitters.

Authors: P Ghosh; R Bose; S K Bhattacharya
Journal: Indian J Med Res Date: 1980-10 Impact factor: 2.375

5. Morphine-induced catalepsy in rat: Role of putative neurotransmitters.

Authors: R Bose; S K Bhattacharya
Journal: Indian J Med Res Date: 1979-08 Impact factor: 2.375

6. Possible interrelationship between the antinociceptive effect of morphine and brain 5-hydroxytryptamine in albino rats.

Authors: A K Sanyal; D N Srivastava; S K Bhattacharya
Journal: Indian J Med Res Date: 1981-05 Impact factor: 2.375

Prostaglandins and central serotonergic activity in the rat.

Review 1. Basic mechanisms of prostaglandin action on autonomic neurotransmission.

2. Stress by restraining potentiates morphine catalepsy in rats.

Review 3. Prostaglandins and the central nervous system.

4. Cannabis-induced catalepsy in mice: role of putative neurotransmitters.

5. Morphine-induced catalepsy in rat: Role of putative neurotransmitters.

6. Possible interrelationship between the antinociceptive effect of morphine and brain 5-hydroxytryptamine in albino rats.

7. Anticonvulsant action of phenobarbitone in rats. Role of brain monoamines.

8. Prostaglandins, aspirin-like drugs and analgesia.

9. Anticonvulsant action of cannabis in the rat: role of brain monoamines.

10. PGD2 effects on rodent behavior and EEG patterns in cats.

1. Prostaglandin D2 inhibits pentylenetetrazole-induced convulsions in rats by a serotonin-mediated mechanism.

2. Role of putative neurotransmitters in bradykinin-induced catalepsy in the rat.