Literature DB >> 24272053

The effect of juglone on cholinergic mechanisms in rat brain synaptosomes.

J R Cooper1, K Piros.   

Abstract

Juglone 5-hydroxy-1,4-napthoquinone exerts three activities on cortical synaptosomal preparations. It inhibits the release of acetylcholine and is an even more potent inhibitor of high-affinity choline transport into synaptosomes. In addition, as has already been shown by others using brain homogenates, juglone inhibits choline acetyltransferase.

Entities:  

Year:  1977        PMID： 24272053     DOI： 10.1007/BF00969356

Source DB:  PubMed          Journal:  Neurochem Res        ISSN： 0364-3190            Impact factor:   3.996


  8 in total

1.  Mechanism of action of beta-bungarotoxin on synaptosomal preparations.

Authors:  I Sen; P A Grantham; J R Cooper
Journal:  Proc Natl Acad Sci U S A       Date:  1976-08       Impact factor: 11.205

2.  Impulse-flow regulation of high affinity choline uptake in brain cholinergic nerve terminals.

Authors:  J R Simon; M G Kuhar
Journal:  Nature       Date:  1975-05-08       Impact factor: 49.962

3.  Inhibition of acetylcholine synthesis by juglone and 4-(1-naphthylvinyl) pyridine.

Authors:  D R Haubrich; P F Wang
Journal:  Biochem Pharmacol       Date:  1976-03-15       Impact factor: 5.858

4.  Protein measurement with the Folin phenol reagent.

Authors:  O H LOWRY; N J ROSEBROUGH; A L FARR; R J RANDALL
Journal:  J Biol Chem       Date:  1951-11       Impact factor: 5.157

5.  Effect of collagenase pretreatment on choline and acetylcholine release from slices of bovine superior cervical sympathetic ganglia.

Authors:  G Sgaragli; J R Cooper
Journal:  Biochem Pharmacol       Date:  1974-02-15       Impact factor: 5.858

6.  Choline uptake systems of rat brain synaptosomes.

Authors:  T Haga; H Noda
Journal:  Biochim Biophys Acta       Date:  1973-01-26

7.  Choline acetyltransferase. Evidence for an acetyl-enzyme reaction intermediate.

Authors:  R Roskoski
Journal:  Biochemistry       Date:  1973-09-11       Impact factor: 3.162

8.  Choline: high-affinity uptake by rat brain synaptosomes.

Authors:  H I Yamamura; S H Snyder
Journal:  Science       Date:  1972-11-10       Impact factor: 47.728
  8 in total

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