Literature DB >> 24271590

In Vivo performance of ophthalmic preparations of betamethasone and phenylephrine hydrochloride in the rabbit eye: Effect of polyvinyl alcohol.

M A Kassem1, M A Attia, F S Habib, A R Mohamed.   

Abstract

The effect of different concentrations of polyvinyl alcohol 14000 and 72000 (PVA 14 and 72) on the activity of betamethasone and phenylephrine hydrochloride in the rabbit eye was investigated. The polymer of higher molecular weight exerts a more pronounced effect at relatively lower viscosities. Effects on the intraocular pressure are more responsive to changes in viscosity than those on pupillary response.

Entities:  

Year:  1986        PMID: 24271590     DOI: 10.1023/A:1016398915965

Source DB:  PubMed          Journal:  Pharm Res        ISSN: 0724-8741            Impact factor:   4.200


  4 in total

1.  Ocular evaluation of polyvinyl alcohol vehicle in rabbits.

Authors:  T F Patton; J R Robinson
Journal:  J Pharm Sci       Date:  1975-08       Impact factor: 3.534

2.  Ocular evaluation of methylcellulose vehicle in albino rabbits.

Authors:  S S Chrai; J R Robinson
Journal:  J Pharm Sci       Date:  1974-08       Impact factor: 3.534

3.  Corneal absorption reinforcement of certain mydriatics.

Authors:  E S Wang; E R Hammarlund
Journal:  J Pharm Sci       Date:  1970-11       Impact factor: 3.534

4.  An in vitro method simulating drug release from viscous eye drops in rabbit and man.

Authors:  C Melis-Decerf; M V Ooteghem
Journal:  J Pharm Pharmacol       Date:  1979-01       Impact factor: 3.765

  4 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.