Literature DB >> 24271353

Formation of multilayered vesicles from water/organic-solvent (w/o) emulsions: theory and practice.

C Pidgeon1, A H Hunt, K Dittrich.   

Abstract

Multilayered liposome (MLV) formation from water/organic-solvent (W/O) emulsions was studied. A fundamental liposome population parameter, the E(ratio), was defined and used to estimate the bilayer number and water spacing in MLV liposomes. MLVs prepared from W/O emulsions have optimum drug entrapment at an emulsion-lipid/emulsion-water ratio of ∼0.33. Drug entrapment is typically 50 to 65% under these optimal conditions.

Entities:  

Year:  1986        PMID： 24271353     DOI： 10.1023/A:1016316730560

Source DB:  PubMed          Journal:  Pharm Res        ISSN： 0724-8741            Impact factor:   4.200


  20 in total

1.  Hydration of phosphatidylocholine. Adsorption isotherm and proton nuclear magnetic resonance studies.

Authors:  D A Wilkinson; H J Morowitz; J H Prestegard
Journal:  Biophys J       Date:  1977-11       Impact factor: 4.033

2.  Novel multilayered lipid vesicles: comparison of physical characteristics of multilamellar liposomes and stable plurilamellar vesicles.

Authors:  S M Gruner; R P Lenk; A S Janoff; M J Ostro
Journal:  Biochemistry       Date:  1985-06-04       Impact factor: 3.162

3.  An interacting spin label study of lateral expansion in dipalmitoyllecithin-cholesterol bilayers.

Authors:  D Marsh
Journal:  Biochim Biophys Acta       Date:  1974-09-23

4.  Dilatometry of dilute suspensions of synthetic lecithin aggregates.

Authors:  D L Melchior; H J Morowitz
Journal:  Biochemistry       Date:  1972-11-21       Impact factor: 3.162

5.  Preparation of unilamellar liposomes of intermediate size (0.1-0.2 mumol) by a combination of reverse phase evaporation and extrusion through polycarbonate membranes.

Authors:  F Szoka; F Olson; T Heath; W Vail; E Mayhew; D Papahadjopoulos
Journal:  Biochim Biophys Acta       Date:  1980-10-02

Review 6.  Preferred conformation and molecular packing of phosphatidylethanolamine and phosphatidylcholine.

Authors:  H Hauser; I Pascher; R H Pearson; S Sundell
Journal:  Biochim Biophys Acta       Date:  1981-06-16

7.  Calculating number and surface area of liposomes in any suspension.

Authors:  C Pidgeon; C A Hunt
Journal:  J Pharm Sci       Date:  1981-02       Impact factor: 3.534

8.  Study of water permeability through phospholipid vesicle membranes by 17O NMR.

Authors:  N Haran; M Shoporer
Journal:  Biochim Biophys Acta       Date:  1976-04-05

9.  Procedure for preparation of liposomes with large internal aqueous space and high capture by reverse-phase evaporation.

Authors:  F Szoka; D Papahadjopoulos
Journal:  Proc Natl Acad Sci U S A       Date:  1978-09       Impact factor: 11.205

10.  Interactions between neutral phospholipid bilayer membranes.

Authors:  L J Lis; M McAlister; N Fuller; R P Rand; V A Parsegian
Journal:  Biophys J       Date:  1982-03       Impact factor: 4.033
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  2 in total

1.  Pulmonary delivery of free and liposomal insulin.

Authors:  F Y Liu; Z Shao; D O Kildsig; A K Mitra
Journal:  Pharm Res       Date:  1993-02       Impact factor: 4.200

2.  Adenosine triphosphate liposomes: encapsulation and distribution studies.

Authors:  G X Xu; X H Xie; F Y Liu; D L Zang; D S Zheng; D J Huang; M X Huang
Journal:  Pharm Res       Date:  1990-05       Impact factor: 4.200
  2 in total

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