Literature DB >> 24271270

Effect of zinc on cadmium influx and toxicity in cultured CHO cells.

P C Huang1, B Smith, P Bohdan, A Corrigan.   

Abstract

Addition of zinc lowers the toxicity level of cadmium in cultured CHO cells. Cell survival and protein synthesis were used to measure the cellular toxicity of cadmium.(109)Cd was used to measure cadmium uptake by the cells. The results suggest that these class IIB transition metals, zinc and cadmium, share a common transport mechanism. Thus, the antagonism appears to involve a reduction in the influx of cadmium due to the presence of zinc.

Entities:  

Year:  1980        PMID： 24271270     DOI： 10.1007/BF02785356

Source DB:  PubMed          Journal:  Biol Trace Elem Res        ISSN： 0163-4984            Impact factor:   3.738


  8 in total

1.  The destructive effect of cadmium ion on testicular tissue and its prevention by zinc.

Authors:  J PARIZEK
Journal:  J Endocrinol       Date:  1957-04       Impact factor: 4.286

2.  Kinetics of cadmium transport in the isolated perfused rat liver.

Authors:  J M Frazier; B S Kingsley
Journal:  Toxicol Appl Pharmacol       Date:  1976-12       Impact factor: 4.219

3.  Cd resistant cells show cross tolerance to Zn++ but not to Hg++.

Authors:  F Haffner; H E Rugstad
Journal:  Acta Pharmacol Toxicol (Copenh)       Date:  1976-05

4.  The relationship of cadmium and zinc in experimental mammalian teratogenesis.

Authors:  V H Ferm; S J Carpenter
Journal:  Lab Invest       Date:  1968-04       Impact factor: 5.662

5.  Mechanisms of zinc, cysteine and selenium protection against cadmium induced vascular injury to mouse testis.

Authors:  S A Gunn; T C Gould; W A Anderson
Journal:  J Reprod Fertil       Date:  1968-02

6.  A cadmium-resistant variant of the Chinese hamster (CHO) cell with increased metallothionein induction capacity.

Authors:  C E Hildebrand; R A Tobey; E W Campbell; M D Enger
Journal:  Exp Cell Res       Date:  1979-12       Impact factor: 3.905

7.  Zinc accumulation and metabolism in primary cultures of adult rat liver cells. Regulation by glucocorticoids.

Authors:  M L Failla; R J Cousins
Journal:  Biochim Biophys Acta       Date:  1978-10-18

8.  Cadmium resistance and content of cadmium-binding protein in two enzyme-deficient mutants of mouse fibroblasts (L-cells).

Authors:  H E Rugstad; T Norseth
Journal:  Biochem Pharmacol       Date:  1978-03-01       Impact factor: 5.858
  8 in total
  8 in total

1.  Toxicity and mutual interactions of cadmium and zinc ions in normal and carcinogen-transformed mouse cells.

Authors:  J M Frenial; J Coppey; J B Little
Journal:  Cell Biol Toxicol       Date:  1986-03       Impact factor: 6.691

2.  Antagonism of cadmium cytotoxicity by differentiation inducers.

Authors:  C Shopsis
Journal:  Cell Biol Toxicol       Date:  1994-06       Impact factor: 6.691

3.  Cadmium and zinc flux in wild-type and cadmium-resistant CHO cells.

Authors:  A J Corrigan; P C Huang
Journal:  Biol Trace Elem Res       Date:  1983-02       Impact factor: 3.738

4.  Cadmium-induced hepatotoxicity in cultured rat hepatocytes as evaluated by morphometric analysis.

Authors:  E M Sorensen; D Acosta
Journal:  In Vitro       Date:  1984-10

5.  Calcium amelioration of cadmium-induced cytotoxicity in cultured rat hepatocytes.

Authors:  E M Sorensen; N K Smith; C S Boecker; D Acosta
Journal:  In Vitro       Date:  1984-10

6.  Comparative studies of zinc metabolism in cultured chinese hamster cells with differing metallothionein-induction capacities.

Authors:  C E Hildebrand; M D Enger; R A Tobey
Journal:  Biol Trace Elem Res       Date:  1980-12       Impact factor: 3.738

7.  Cellular uptake of cadmium and zinc.

Authors:  A J Corrigan; P C Huang
Journal:  Biol Trace Elem Res       Date:  1981-09       Impact factor: 3.738

8.  Effects of trace metal profiles characteristic for autism on synapses in cultured neurons.

Authors:  Simone Hagmeyer; Katharina Mangus; Tobias M Boeckers; Andreas M Grabrucker
Journal:  Neural Plast       Date:  2015-02-23       Impact factor: 3.599
  8 in total

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