Literature DB >> 2427101

Presence of I-region gene products on the cells and their products of the dengue virus-induced suppressor pathway.

M I Shukla, U C Chaturvedi.   

Abstract

We have studied both the cells and the suppressor factors of the dengue virus-induced suppressor pathway for the presence of I-region gene products. The suppressor activity of Ts1, Ts2 and Ts3 cells was abrogated by treatment with anti I-Jk or I-Ak anti-sera and complement. Both the suppressor factors were absorbed out by anti I-Jk and I-Ak immunosorbent columns. The activity of the suppressor factor was abolished by treatment with anti I-Jk antisera. Macrophage presentation of suppressor factor to precursors of Ts2 cells was abolished by treatment with anti I-Ak antisera and complement but not by anti I-Jk antisera. Thus I-region gene products were found throughout the dengue virus induced suppressor pathway.

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Year:  1986        PMID： 2427101      PMCID： PMC2013043     

Source DB:  PubMed          Journal:  Br J Exp Pathol        ISSN： 0007-1021


  15 in total

Review 1.  Interaction between antigen-presenting cells and primed T lymphocytes: an assessment of Ir gene expression in the antigen-presenting cell.

Authors:  R H Schwartz; A Yano; W E Paul
Journal:  Immunol Rev       Date:  1978       Impact factor: 12.988

2.  Host defence mechanisms against dengue virus infection of mice.

Authors:  U C Chaturvedi; P Tandon; A Mathur; A Kumar
Journal:  J Gen Virol       Date:  1978-05       Impact factor: 3.891

3.  Major histocompatibility gene complex (MHC)-coded determinants on antigen-specific suppressor factor for delayed-type hypersensitivity and surface phenotypes of cells producing the factor.

Authors:  F Y Liew; D Y Sia; C R Parish; I F McKenzie
Journal:  Eur J Immunol       Date:  1980-04       Impact factor: 5.532

4.  Suppressor cell induction in vitro. VI. Production of suppressor factors to synthetic polypeptides GAT and (T,G)-A--L from cells of responder and nonresponder mice.

Authors:  S Kontianen; S Howie; P H Maurer; M Feldmann
Journal:  J Immunol       Date:  1979-01       Impact factor: 5.422

5.  Transmission of dengue virus-induced suppressor signal from macrophage to lymphocyte occurs by cell contact.

Authors:  M I Shukla; U C Chaturvedi
Journal:  Br J Exp Pathol       Date:  1983-02

Review 6.  Genetic and functional analysis of the Ia antigens: their possible role in regulating the immune response.

Authors:  H O McDevitt; T L Delovitch; J L Press; D B Murphy
Journal:  Transplant Rev       Date:  1976

7.  Production of cytotoxic factor in the spleen of dengue virus-infected mice.

Authors:  U C Chaturvedi; A Bhargava; A Mathur
Journal:  Immunology       Date:  1980-08       Impact factor: 7.397

8.  Immunosuppressive factor(s) extracted from lymphoid cells of nonresponder mice primed with L-glutamic acid60-L-alanine30-L-tyrosine10 (GAT) III. Immunochemical properties of the GAT-specific suppressive factor.

Authors:  J Theze; J A Kapp; B Benacerraf
Journal:  J Exp Med       Date:  1977-04-01       Impact factor: 14.307

9.  The I-J subregion codes for determinats on suppressor factor(s) which limit the contact sensitivity response to picryl chloride.

Authors:  M I Greene; A Pierres; M E Dorf; B Benacerraf
Journal:  J Exp Med       Date:  1977-07-01       Impact factor: 14.307

10.  In vivo effects of anti-Ia alloantisera. I. Elimination of specific suppression by in vivo administration of antisera specific for I-J controlled determinants.

Authors:  M Pierres; R N Germain; M E Dorf; B Benacerraf
Journal:  J Exp Med       Date:  1978-03-01       Impact factor: 14.307
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  1 in total

1.  Variable effects of dengue virus-induced cytotoxic factors on different subpopulations of macrophages.

Authors:  U C Chaturvedi; R Nagar; L Gulati; A Mathur
Journal:  Immunology       Date:  1987-07       Impact factor: 7.397
  1 in total

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