Literature DB >> 24270748

Prenatal screening for major congenital heart disease: assessing performance by combining national cardiac audit with maternity data.

Helena M Gardiner1, Alexander Kovacevic, Laila B van der Heijden, Patricia W Pfeiffer, Rodney Cg Franklin, John L Gibbs, Ian E Averiss, Joan M Larovere.   

Abstract

OBJECTIVE: Determine maternity hospital and lesion-specific prenatal detection rates of major congenital heart disease (mCHD) for hospitals referring prenatally and postnatally to one Congenital Cardiac Centre, and assess interhospital relative performance (relative risk, RR).
METHODS: We manually linked maternity data (3 hospitals prospectively and another 16 retrospectively) with admissions, fetal diagnostic and surgical cardiac data from one Congenital Cardiac Centre. This Centre submits verified information to National Institute for Cardiovascular Outcomes Research (NICOR-Congenital), which publishes aggregate antenatal diagnosis data from infant surgical procedures. We included 120 198 unselected women screened prospectively over 11 years in 3 maternity hospitals (A, B, C). Hospital A: colocated with fetal medicine, proactive superintendent, on-site training, case-review and audit, hospital B: on-site training, proactive superintendent, monthly telemedicine clinics, and hospital C: sonographers supported by local obstetrician. We then studied 321 infants undergoing surgery for complete transposition (transposition of the great arteries (TGA), n=157) and isolated aortic coarctation (CoA, n=164) screened in hospitals A, B, C prospectively, and 16 hospitals retrospectively.
RESULTS: 385 mCHD recorded prospectively from 120 198 (3.2/1000) screened women in 3 hospitals. Interhospital relative performance (RR) in Hospital A:1.68 (1.4 to 2.0), B:0.70 (0.54 to 0.91), C:0.65 (0.5 to 0.8). Standardised prenatal detection rates (funnel plots) demonstrating inter-hospital variation across 19 hospitals for TGA (37%, 0.00 to 0.81) and CoA (34%, 0.00 to 1.06).
CONCLUSIONS: Manually linking data sources produced hospital-specific and lesion-specific prenatal mCHD detection rates. More granular, rather than aggregate, data provides meaningful feedback to improve screening performance. Automatic maternal and infant record linkage on a national scale, requires verified, prospective maternity audit and integration of health information systems.

Entities:  

Keywords:  Congenital Heart Disease

Mesh:

Year:  2013        PMID: 24270748     DOI: 10.1136/heartjnl-2013-304640

Source DB:  PubMed          Journal:  Heart        ISSN: 1355-6037            Impact factor:   5.994


  15 in total

1.  Physician Barriers and Facilitators for Screening for Congenital Heart Disease With Routine Obstetric Ultrasound: A National United States Survey.

Authors:  Nelangi M Pinto; Kevin A Henry; William A Grobman; Amen Ness; Stephen Miller; Sarah Ellestad; Nina Gotteiner; Theresa Tacy; Guo Wei; L LuAnn Minich; Anita Y Kinney
Journal:  J Ultrasound Med       Date:  2019-12-24       Impact factor: 2.153

2.  Prenatal Detection of Coarctation of the Aorta in a Non-selected Population: A Prospective Analysis of 10 Years of Experience.

Authors:  I Durand; G Deverriere; C Thill; A S Lety; C Parrod; N David; E Barre; T Hazelzet
Journal:  Pediatr Cardiol       Date:  2015-04-07       Impact factor: 1.655

3.  Low rate of prenatal diagnosis among neonates with critical aortic stenosis: insight into the natural history in utero.

Authors:  L R Freud; A Moon-Grady; M C Escobar-Diaz; N L Gotteiner; L T Young; D B McElhinney; W Tworetzky
Journal:  Ultrasound Obstet Gynecol       Date:  2015-01-28       Impact factor: 7.299

4.  Live-Born Major Congenital Heart Disease in Denmark: Incidence, Detection Rate, and Termination of Pregnancy Rate From 1996 to 2013.

Authors:  Rebekka Lytzen; Niels Vejlstrup; Jesper Bjerre; Olav Bjørn Petersen; Stine Leenskjold; James Keith Dodd; Finn Stener Jørgensen; Lars Søndergaard
Journal:  JAMA Cardiol       Date:  2018-09-01       Impact factor: 14.676

Review 5.  Hypertension in Coarctation of the Aorta: Challenges in Diagnosis in Children.

Authors:  Trisha V Vigneswaran; Manish D Sinha; Israel Valverde; John M Simpson; Marietta Charakida
Journal:  Pediatr Cardiol       Date:  2017-10-17       Impact factor: 1.655

6.  Prenatal diagnosis of transposition of the great arteries over a 20-year period: improved but imperfect.

Authors:  M C Escobar-Diaz; L R Freud; A Bueno; D W Brown; K G Friedman; D Schidlow; S Emani; P J Del Nido; W Tworetzky
Journal:  Ultrasound Obstet Gynecol       Date:  2015-04-30       Impact factor: 7.299

Review 7.  Prenatal screening for structural congenital heart disease.

Authors:  Lindsey E Hunter; John M Simpson
Journal:  Nat Rev Cardiol       Date:  2014-03-25       Impact factor: 32.419

8.  Nordic pulse oximetry screening--implementation status and proposal for uniform guidelines.

Authors:  Anne de-Wahl Granelli; Alf Meberg; Tiina Ojala; Jesper Steensberg; Gylfi Oskarsson; Mats Mellander
Journal:  Acta Paediatr       Date:  2014-08-24       Impact factor: 2.299

Review 9.  Universal Pulse Oximetry Screening for Early Detection of Critical Congenital Heart Disease.

Authors:  Praveen Kumar
Journal:  Clin Med Insights Pediatr       Date:  2016-06-01

10.  Length to width ratio of the ductus venosus in simple screening for fetal congenital heart diseases in the second trimester.

Authors:  Wei-Hsiu Chiu; Shy-Ming Lee; Tao-Hsin Tung; Xiao-Mei Tang; Ren-Shyan Liu; Ran-Chou Chen
Journal:  Medicine (Baltimore)       Date:  2016-09       Impact factor: 1.889

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