Literature DB >> 24270310

Anhedonia in substance use disorders: a systematic review of its nature, course and clinical correlates.

Joshua B B Garfield1, Dan I Lubman, Murat Yücel.   

Abstract

OBJECTIVE: There is growing evidence that anhedonia is a commonly experienced symptom among substance-using populations. This systematic review synthesises findings across a range of substances to address questions regarding the time course of anhedonia, how anhedonia relates to other symptoms of substance dependence and whether it is similarly prevalent across all addictive drugs.
METHOD: A literature search was conducted on PubMed, PsycINFO and MEDLINE, yielding 32 studies that used self-report measures of anhedonia among participants with a history of a substance abuse, dependence or long-term daily use of addictive substances.
RESULTS: Findings from these studies indicate that anhedonia (1) is elevated in samples dependent on a range of substances; (2) typically appears as a consequence of substance abuse or dependence, and diminishes with abstinence; and (3) predicts increased drug cravings and the likelihood of relapse in those attempting abstinence.
CONCLUSIONS: The common experience of anhedonia in substance-dependent populations, and its relationship to relapse, emphasises the importance of developing therapeutic interventions that specifically target anhedonia in the treatment of all substance use disorders.

Entities:  

Keywords:  Anhedonia; addiction; recovery; substance abuse; substance dependence

Mesh:

Year:  2013        PMID: 24270310     DOI: 10.1177/0004867413508455

Source DB:  PubMed          Journal:  Aust N Z J Psychiatry        ISSN: 0004-8674            Impact factor:   5.744


  47 in total

1.  Intact responses to non-drug rewards in long-term opioid maintenance treatment.

Authors:  Marie Eikemo; Philipp P Lobmaier; Mads L Pedersen; Nikolaj Kunøe; Anna Maria Matziorinis; Siri Leknes; Monica Sarfi
Journal:  Neuropsychopharmacology       Date:  2019-03-31       Impact factor: 7.853

2.  The adverse health effects and harms related to marijuana use: an overview review.

Authors:  K Ally Memedovich; Laura E Dowsett; Eldon Spackman; Tom Noseworthy; Fiona Clement
Journal:  CMAJ Open       Date:  2018-08-16

3.  Structural connectivity and risk for anhedonia after trauma: A prospective study and replication.

Authors:  Negar Fani; Vasiliki Michopoulos; Sanne J H van Rooij; Cherita Clendinen; Raven A Hardy; Tanja Jovanovic; Barbara O Rothbaum; Kerry J Ressler; Jennifer S Stevens
Journal:  J Psychiatr Res       Date:  2019-05-14       Impact factor: 4.791

4.  Negative affect and emotion dysregulation among people who inject drugs: An ecological momentary assessment study.

Authors:  Mary Ellen Mackesy-Amiti; Geri Donenberg
Journal:  Psychol Addict Behav       Date:  2020-04-09

5.  N-Methyl-d-aspartate receptor co-agonist availability affects behavioral and neurochemical responses to cocaine: insights into comorbid schizophrenia and substance abuse.

Authors:  Matthew D Puhl; Rajeev I Desai; Shunsuke Takagi; Kendall T Presti; Michelle R Doyle; Rachel J Donahue; Samantha M Landino; Jack Bergman; William A Carlezon; Joseph T Coyle
Journal:  Addict Biol       Date:  2017-11-23       Impact factor: 4.280

6.  Evidence of anhedonia and differential reward processing in prefrontal cortex among post-withdrawal patients with prescription opiate dependence.

Authors:  A S Huhn; R E Meyer; J D Harris; H Ayaz; E Deneke; D M Stankoski; S C Bunce
Journal:  Brain Res Bull       Date:  2015-12-19       Impact factor: 4.077

7.  Ecological momentary assessment of affect and craving in patients in treatment for prescription opioid dependence.

Authors:  Andrew S Huhn; Jonathan Harris; H Harrington Cleveland; David M Lydon; Dean Stankoski; Michael J Cleveland; Erin Deneke; Scott C Bunce
Journal:  Brain Res Bull       Date:  2016-02-11       Impact factor: 4.077

8.  Anhedonia Is Associated with Poorer Outcomes in Contingency Management for Cocaine Use Disorder.

Authors:  Margaret C Wardle; Jessica N Vincent; Robert Suchting; Charles E Green; Scott D Lane; Joy M Schmitz
Journal:  J Subst Abuse Treat       Date:  2016-09-09

9.  Symptoms of anhedonia, not depression, predict the outcome of treatment of cocaine dependence.

Authors:  Paul Crits-Christoph; Steven Wadden; Averi Gaines; Agnes Rieger; Robert Gallop; James R McKay; Mary Beth Connolly Gibbons
Journal:  J Subst Abuse Treat       Date:  2018-06-21

10.  COMT Val(158) Met genotype is associated with reward learning: a replication study and meta-analysis.

Authors:  N S Corral-Frías; D A Pizzagalli; J M Carré; L J Michalski; Y S Nikolova; R H Perlis; J Fagerness; M R Lee; E Drabant Conley; T M Lancaster; S Haddad; A Wolf; J W Smoller; A R Hariri; R Bogdan
Journal:  Genes Brain Behav       Date:  2016-06       Impact factor: 3.449

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