Literature DB >> 24270163

AlloDerm with split-thickness skin graft for coverage of the forearm free flap donor site.

Jacob L Wester1, Amy L Pittman, Robert H Lindau, Mark K Wax.   

Abstract

OBJECTIVE: Major causes of donor site morbidity after free flap harvest are lack of split-thickness skin graft (STSG) take and tendon exposure. Long-term cosmesis remains poor. AlloDerm has shown cosmetically better donor site healing, albeit prolonged healing. We sought to evaluate the use of STSG with AlloDerm compared with STSG alone. STUDY
DESIGN: Case series with chart review.
SETTING: Academic tertiary care medical center. METHODS AND
SUBJECTS: Institutional review board-approved study. Microvascular database queried from 2002 to 2012. Subjects with forearm free flaps and either AlloDerm + STSG or STSG alone for donor site reconstruction were included. Morbidity outcomes were compared.
RESULTS: Eighty patients (50 male, 30 female) received AlloDerm + STSG at the donor site. Major and minor donor site complications were 15.0% and 18.8% in the AlloDerm + STSG group compared with 10.2% and 16.9% in the STSG-only group (P = .30 and P = .72), respectively. Complete STSG loss (5.0% vs 3.0%, P = .48), tendon exposure (5.0% vs 5.4%, P = 1.0), functional impairment (2.5% vs 1.8%, P = .66), infection (8.8% vs 9.6%, P = 1.0), hematoma/seroma (5.0% vs 3.6%, P = .73), and paresthesia (1.3% vs 3.6%, P = .43) were not significant. No patients required a second STSG after loss in the AlloDerm + STSG group compared with 60% (P = .17). Cosmetic results were superior in the AlloDerm + STSG group as rated by the surgeon (3.5 vs 2.6, P = .03) and patients (3.7 vs 2.9, P = .05) on a scale of 1 to 5.
CONCLUSION: Our results suggest that the use of AlloDerm with STSG can provide thicker coverage of the forearm defect, with minimal donor site morbidity and superior cosmetic results compared with STSG alone.

Entities:  

Keywords:  AlloDerm; donor site; free flap; head and neck; microvascular; radial forearm

Mesh:

Substances:

Year:  2013        PMID: 24270163     DOI: 10.1177/0194599813513713

Source DB:  PubMed          Journal:  Otolaryngol Head Neck Surg        ISSN: 0194-5998            Impact factor:   3.497


  8 in total

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Journal:  Eur Arch Otorhinolaryngol       Date:  2018-02-26       Impact factor: 2.503

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3.  The rapid inactivation of porcine skin by applying high hydrostatic pressure without damaging the extracellular matrix.

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4.  Double-layered collagen graft to the radial forearm free flap donor sites without skin graft.

Authors:  Tae-Jun Park; Hong-Joon Kim; Kang-Min Ahn
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5.  Long-term follow-up of donor site morbidity after defect coverage with Integra following radial forearm flap elevation.

Authors:  Anna Wirthmann; Juliane C Finke; Pietro Giovanoli; Nicole Lindenblatt
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Authors:  Pietro Gentile; Simone Garcovich
Journal:  Int J Mol Sci       Date:  2021-02-03       Impact factor: 5.923

8.  Negative-pressure wound therapy combined with artificial dermis (Terudermis) followed by split-thickness skin graft might be an effective treatment option for wounds exposing tendon and bone: A retrospective observation study.

Authors:  Kuo-Feng Hsu; Yu-Lung Chiu; Hao Yu Chiao; Chun-Yu Chen; Chun-Kai Chang; Chien-Ju Wu; Yi-Jen Peng; Chih-Hsin Wang; Niann-Tzyy Dai; Shyi-Gen Chen; Yuan-Sheng Tzeng
Journal:  Medicine (Baltimore)       Date:  2021-04-09       Impact factor: 1.817

  8 in total

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