Liliana Dell'osso1, Paolo Stratta2, Ciro Conversano1, Enrico Massimetti1, Kareen K Akiskal3, Hagop S Akiskal3, Alessandro Rossi2, Claudia Carmassi4. 1. Section of Psychiatry, Department of Clinical and Experimental Medicine, University of Pisa, Pisa, Italy. 2. Section of Psychiatry, Department of Experimental Medicine, University of L'Aquila, Italy, L'Aquila, Italy. 3. International Mood Center, University of California, San Diego, CA, USA. 4. Section of Psychiatry, Department of Clinical and Experimental Medicine, University of Pisa, Pisa, Italy. Electronic address: ccarmassi@gmail.com.
Abstract
BACKGROUND: Bipolar patients seem to be at high risk of trauma exposure and, when exposed, of PTSD. When comorbid, PTSD has shown a negative impact on the course of the bipolar illness. Conversely, a correlation between even manic symptoms and an increased risk for suicide has also been reported in PTSD patients. The aim of this study was to investigate the relationships between lifetime mood spectrum symptoms and PTSD in a sample of earthquake survivors. METHODS: A total of 475 young adults who survived the L'Aquila 2009 earthquake, 21months earlier, were assessed by the Moods Spectrum-Self Report (MOODS-SR) and the Trauma and Loss Spectrum Self Report (TALS-SR). RESULTS: Significantly higher MOODS-SR and TALS-SR domain scores were found in PTSD survivors compared to those without. The mood depressive (O.R.=1.17, 95% CI: 1.10-1.25), cognition depressive (O.R.=1.07, 95% CI: 1.01-1.14) and energy manic (O.R.=1.13, 95% CI: 1.02-1.25) MOODS-SR domains were significantly associated with an increased likelihood of PTSD. CONCLUSIONS: Our data corroborate the strong relationship between mood disorder and PTSD highlighting a relationship between lifetime depressive and manic symptoms and PTSD, with a particular impact of the latter on the number of traumatic exposures and maladaptive behaviors.
BACKGROUND: Bipolar patients seem to be at high risk of trauma exposure and, when exposed, of PTSD. When comorbid, PTSD has shown a negative impact on the course of the bipolar illness. Conversely, a correlation between even manic symptoms and an increased risk for suicide has also been reported in PTSDpatients. The aim of this study was to investigate the relationships between lifetime mood spectrum symptoms and PTSD in a sample of earthquake survivors. METHODS: A total of 475 young adults who survived the L'Aquila 2009 earthquake, 21months earlier, were assessed by the Moods Spectrum-Self Report (MOODS-SR) and the Trauma and Loss Spectrum Self Report (TALS-SR). RESULTS: Significantly higher MOODS-SR and TALS-SR domain scores were found in PTSD survivors compared to those without. The mood depressive (O.R.=1.17, 95% CI: 1.10-1.25), cognition depressive (O.R.=1.07, 95% CI: 1.01-1.14) and energy manic (O.R.=1.13, 95% CI: 1.02-1.25) MOODS-SR domains were significantly associated with an increased likelihood of PTSD. CONCLUSIONS: Our data corroborate the strong relationship between mood disorder and PTSD highlighting a relationship between lifetime depressive and manic symptoms and PTSD, with a particular impact of the latter on the number of traumatic exposures and maladaptive behaviors.
Authors: Claudia Carmassi; Paolo Stratta; Gabriele Massimetti; Carlo Antonio Bertelloni; Ciro Conversano; Ivan Mirko Cremone; Mario Miccoli; Angelo Baggiani; Alessandro Rossi; Liliana Dell'Osso Journal: Ann Gen Psychiatry Date: 2014-11-18 Impact factor: 3.455
Authors: Liliana Dell'Osso; Ciro Conversano; Martina Corsi; Carlo A Bertelloni; Ivan M Cremone; Barbara Carpita; Manuel G Carbone; Camilla Gesi; Claudia Carmassi Journal: Case Rep Psychiatry Date: 2018-02-22
Authors: Claudia Carmassi; Camilla Gesi; Martina Corsi; Ivan M Cremone; Carlo A Bertelloni; Enrico Massimetti; Maria Cristina Olivieri; Ciro Conversano; Massimo Santini; Liliana Dell'Osso Journal: Ann Gen Psychiatry Date: 2018-05-04 Impact factor: 3.455
Authors: Claudia Carmassi; Martina Corsi; Carlo Antonio Bertelloni; Barbara Carpita; Camilla Gesi; Virginia Pedrinelli; Gabriele Massimetti; Diego Giampietro Peroni; Alice Bonuccelli; Alessandro Orsini; Liliana Dell'Osso Journal: Neuropsychiatr Dis Treat Date: 2018-05-25 Impact factor: 2.570