Literature DB >> 24269165

Preparation of 8-hydroxyquinoline derivatives as potential antibiotics against Staphylococcus aureus.

Kim-Hung Lam1, Roberto Gambari2, Kenneth Ka-Ho Lee3, Yi-Xin Chen4, Stanton Hon-Lung Kok3, Raymond Siu-Ming Wong3, Fung-Yi Lau3, Chor-Hing Cheng5, Wai-Yeung Wong6, Zhao-Xiang Bian7, Albert Sun-Chi Chan8, Johnny Cheuk-On Tang9, Chung-Hin Chui10.   

Abstract

This work describes the preparation of quinoline compounds as possible anti-bacterial agents. The synthesized quinoline derivatives show anti-bacterial activity towards Staphylococcus aureus. It is interesting to observe that the synthetic 5,7-dibromo-2-methylquinolin-8-ol (4) shows a similar minimum inhibitory concentration of 6.25μg/mL as compared to that of methicillin (3.125μg/mL) against Staphylococcus aureus.
Copyright © 2013 Elsevier Ltd. All rights reserved.

Entities:  

Keywords:  Antibacterial agents; Antibiotics; Quinolines; Staphylococcus aureus

Mesh：

Substances：

Year:  2013        PMID： 24269165     DOI： 10.1016/j.bmcl.2013.10.072

Source DB:  PubMed          Journal:  Bioorg Med Chem Lett        ISSN： 0960-894X            Impact factor:   2.823


  9 in total

1.  Ionic Liquid as an Efficient Medium for the Synthesis of Quinoline Derivatives via α-Chymotrypsin-Catalyzed Friedländer Condensation.

Authors:  Zhang-Gao Le; Meng Liang; Zhong-Sheng Chen; Sui-Hong Zhang; Zong-Bo Xie
Journal:  Molecules       Date:  2017-05-08       Impact factor: 4.411

2.  8-Hydroxyquinolines are bactericidal against Mycobacterium tuberculosis.

Authors:  Joshua O Odingo; Julie V Early; Jake Smith; James Johnson; Mai A Bailey; Megan Files; Junitta Guzman; Juliane Ollinger; Aaron Korkegian; Anuradha Kumar; Yulia Ovechkina; Tanya Parish
Journal:  Drug Dev Res       Date:  2019-03-20       Impact factor: 4.360

3.  Development of an efficient, one-pot, multicomponent protocol for synthesis of 8-hydroxy-4-phenyl-1,2-dihydroquinoline derivatives.

Authors:  Rukhsana Tabassum; Muhammad Ashfaq; Hiroyuki Oku
Journal:  J Heterocycl Chem       Date:  2020-12-02       Impact factor: 2.035

4.  Synthesis and anti-phytopathogenic activity of 8-hydroxyquinoline derivatives.

Authors:  Xiao-Dan Yin; Yu Sun; Raymond Kobla Lawoe; Guan-Zhou Yang; Ying-Qian Liu; Xiao-Fei Shang; Hua Liu; Yu-Dong Yang; Jia-Kai Zhu; Xiao-Ling Huang
Journal:  RSC Adv       Date:  2019-09-24       Impact factor: 4.036

5.  Synthesis of hexahydrofuro[3,2-c]quinoline, a martinelline type analogue and investigation of its biological activity.

Authors:  P-Y Chung; J C-O Tang; C-H Cheng; Z-X Bian; W-Y Wong; K-H Lam; C-H Chui
Journal:  Springerplus       Date:  2016-03-03

6.  Anti-cancer Effects of a Novel Quinoline Derivative 83b1 on Human Esophageal Squamous Cell Carcinoma through Down-Regulation of COX-2 mRNA and PGE2.

Authors:  Ivan Ho Yuen Pun; Dessy Chan; Sau Hing Chan; Po Yee Chung; Yuan Yuan Zhou; Simon Law; Alfred King Yin Lam; Chung Hin Chui; Albert Sun Chi Chan; Kim Hung Lam; Johnny Cheuk On Tang
Journal:  Cancer Res Treat       Date:  2016-07-18       Impact factor: 4.679

7.  Antiviral Activity of Novel Quinoline Derivatives against Dengue Virus Serotype 2.

Authors:  Carolina de la Guardia; David E Stephens; Hang T Dang; Mario Quijada; Oleg V Larionov; Ricardo Lleonart
Journal:  Molecules       Date:  2018-03-16       Impact factor: 4.411

8.  Derivatives (halogen, nitro and amino) of 8-hydroxyquinoline with highly potent antimicrobial and antioxidant activities.

Authors:  Rungrot Cherdtrakulkiat; Somchai Boonpangrak; Nujarin Sinthupoom; Supaluk Prachayasittikul; Somsak Ruchirawat; Virapong Prachayasittikul
Journal:  Biochem Biophys Rep       Date:  2016-03-24

9.  (Iso)Quinoline-Artemisinin Hybrids Prepared through Click Chemistry: Highly Potent Agents against Viruses.

Authors:  Aysun Çapcı; Mélanie M Lorion; Christina Mai; Friedrich Hahn; Jan Hodek; Christina Wangen; Jan Weber; Manfred Marschall; Lutz Ackermann; Svetlana B Tsogoeva
Journal:  Chemistry       Date:  2020-08-18       Impact factor: 5.020
  9 in total

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