Kelly R Daniels1, Grace C Lee1, Christopher R Frei2. 1. College of Pharmacy, University of Texas at Austin, Austin, TX; Pharmacotherapy Education and Research Center, University of Texas Health Science Center at San Antonio, San Antonio, TX. 2. College of Pharmacy, University of Texas at Austin, Austin, TX; Pharmacotherapy Education and Research Center, University of Texas Health Science Center at San Antonio, San Antonio, TX. Electronic address: freic@uthscsa.edu.
Abstract
BACKGROUND: Catheter-associated urinary tract infections (CAUTIs) have become a major public health concern in the United States. This study provides national estimates of CAUTI incidence, mortality, and associated hospital length of stay (LOS) over a 10-year period. METHODS: This was a retrospective analysis of the National Hospital Discharge Surveys from 2001 to 2010. Adults age ≥18 years with an International Classification of Diseases, Ninth Revision, Clinical Modification (ICD-9-CM) procedure code for urinary catheter placement or other major procedure were included. Urinary tract infections were identified by ICD-9-CM code. Data weights were applied to derive national estimates. Predictors of CAUTI were identified using a logistic regression model. RESULTS: These data represent 70.4 million catheterized patients, 3.8 million of whom developed a CAUTI. The incidence of CAUTIs decreased from 9.4 cases/100 catheterizations in 2001 to 5.3 cases/100 catheterizations in 2010. Mortality in patients with a CAUTI declined from 5.4% in 2001 to 3.7% in 2010. Median (interquartile range [IQR]) hospital LOS also declined, from 9 days (IQR, 5-16 days) in 2001 to 7 days (IQR, 4-12 days) in 2010. Independent predictors of CAUTI included female sex, emergency hospital admission, transfer from another facility, and Medicaid payment (P < .0001 for all variables). CONCLUSIONS: The incidence of CAUTIs in US hospitals declined over the study period. Furthermore, patients with these infections experienced lower hospital mortality and shorter hospital LOS.
BACKGROUND: Catheter-associated urinary tract infections (CAUTIs) have become a major public health concern in the United States. This study provides national estimates of CAUTI incidence, mortality, and associated hospital length of stay (LOS) over a 10-year period. METHODS: This was a retrospective analysis of the National Hospital Discharge Surveys from 2001 to 2010. Adults age ≥18 years with an International Classification of Diseases, Ninth Revision, Clinical Modification (ICD-9-CM) procedure code for urinary catheter placement or other major procedure were included. Urinary tract infections were identified by ICD-9-CM code. Data weights were applied to derive national estimates. Predictors of CAUTI were identified using a logistic regression model. RESULTS: These data represent 70.4 million catheterized patients, 3.8 million of whom developed a CAUTI. The incidence of CAUTIs decreased from 9.4 cases/100 catheterizations in 2001 to 5.3 cases/100 catheterizations in 2010. Mortality in patients with a CAUTI declined from 5.4% in 2001 to 3.7% in 2010. Median (interquartile range [IQR]) hospital LOS also declined, from 9 days (IQR, 5-16 days) in 2001 to 7 days (IQR, 4-12 days) in 2010. Independent predictors of CAUTI included female sex, emergency hospital admission, transfer from another facility, and Medicaid payment (P < .0001 for all variables). CONCLUSIONS: The incidence of CAUTIs in US hospitals declined over the study period. Furthermore, patients with these infections experienced lower hospital mortality and shorter hospital LOS.
Authors: Chelsie E Armbruster; Sara N Smith; Alexandra O Johnson; Valerie DeOrnellas; Kathryn A Eaton; Alejandra Yep; Lona Mody; Weisheng Wu; Harry L T Mobley Journal: Infect Immun Date: 2017-01-26 Impact factor: 3.441
Authors: Chelsie E Armbruster; Valerie S Forsyth; Alexandra O Johnson; Sara N Smith; Ashley N White; Aimee L Brauer; Brian S Learman; Lili Zhao; Weisheng Wu; Mark T Anderson; Michael A Bachman; Harry L T Mobley Journal: PLoS Pathog Date: 2019-04-22 Impact factor: 6.823