Jérôme Rivory1, Vincent Lépilliez2, Rodica Gincul2, Olivier Guillaud2, Mélanie Vallin1, Yves Bouffard3, Pierre Sagnard3, Thierry Ponchon1, Jérôme Dumortier4. 1. Hospices civils de Lyon, hôpital Edouard-Herriot, fédération des spécialités digestives, Lyon, France; Université Claude-Bernard Lyon-1, Villeurbanne, France. 2. Hospices civils de Lyon, hôpital Edouard-Herriot, fédération des spécialités digestives, Lyon, France. 3. Hospices civils de Lyon, hôpital Edouard-Herriot, département d'anesthésie-réanimation, Lyon, France. 4. Hospices civils de Lyon, hôpital Edouard-Herriot, fédération des spécialités digestives, Lyon, France; Université Claude-Bernard Lyon-1, Villeurbanne, France. Electronic address: jerome.dumortier@chu-lyon.fr.
Abstract
BACKGROUND AND AIMS: With small diameter endoscopes, transnasal esophagogastroduodenoscopy (t-EGD) is routinely performed. The aim of this prospective observational study was to evaluate the role of t-EGD for upper gastrointestinal bleeding (UGIB). PATIENTS AND METHODS: One hundred and forty-five consecutive patients (mean age, 66±18.4 years) with suspicion of UGIB were classified a priori into 3 groups according to initial clinical presentation: (1) intensive care unit with EGD under sedation, (2) endoscopy unit with EGD under transient sedation and (3) unsedated t-EGD as "first look". Demographic, clinical and biological parameters, Rockall and Blatchford scores, endoscopic diagnosis and treatment, and outcome were analysed. RESULTS: Unsedated t-EGD was attempted in 89 patients, performed in 52 (5 failures, 28 contraindications) and the procedure was converted under sedation for 2 patients. Based on ASA classification, clinical (blood pressure, hemodynamical failure) and biological variables (hemoglobin, platelets, creatinine), these patients were less severe than in the other groups. Pre-endoscopic Rockall and Blatchford scores were significantly lower in this group. More patients in this group presented significant cardiovascular co-morbidity (47.2%), taking aspirin, clopidogrel and/or anticoagulant. CONCLUSIONS: Our results strongly support that "first look" unsedated t-EGD can avoid unnecessary sedation in selected patients with UGIB, presenting a low probability for endoscopic haemostatic treatment and high sedation risks.
BACKGROUND AND AIMS: With small diameter endoscopes, transnasal esophagogastroduodenoscopy (t-EGD) is routinely performed. The aim of this prospective observational study was to evaluate the role of t-EGD for upper gastrointestinal bleeding (UGIB). PATIENTS AND METHODS: One hundred and forty-five consecutive patients (mean age, 66±18.4 years) with suspicion of UGIB were classified a priori into 3 groups according to initial clinical presentation: (1) intensive care unit with EGD under sedation, (2) endoscopy unit with EGD under transient sedation and (3) unsedated t-EGD as "first look". Demographic, clinical and biological parameters, Rockall and Blatchford scores, endoscopic diagnosis and treatment, and outcome were analysed. RESULTS: Unsedated t-EGD was attempted in 89 patients, performed in 52 (5 failures, 28 contraindications) and the procedure was converted under sedation for 2 patients. Based on ASA classification, clinical (blood pressure, hemodynamical failure) and biological variables (hemoglobin, platelets, creatinine), these patients were less severe than in the other groups. Pre-endoscopic Rockall and Blatchford scores were significantly lower in this group. More patients in this group presented significant cardiovascular co-morbidity (47.2%), taking aspirin, clopidogrel and/or anticoagulant. CONCLUSIONS: Our results strongly support that "first look" unsedated t-EGD can avoid unnecessary sedation in selected patients with UGIB, presenting a low probability for endoscopic haemostatic treatment and high sedation risks.
Authors: Samuel Lim; Hasan Nadim Haboubi; Simon H C Anderson; Patrick Dawson; Ana Paula Machado; Edna Mangsat; Sara Santos; Terry Wong; Sebastian Zeki; Jason Dunn Journal: Frontline Gastroenterol Date: 2022-05-31
Authors: Nathalie Nguyen; William J Lavery; Kelley E Capocelli; Clinton Smith; Emily M DeBoer; Robin Deterding; Jeremy D Prager; Kristina Leinwand; Greg E Kobak; Robert E Kramer; Calies Menard-Katcher; Glenn T Furuta; Dan Atkins; David Fleischer; Matthew Greenhawt; Joel A Friedlander Journal: Clin Gastroenterol Hepatol Date: 2019-01-29 Impact factor: 11.382