Literature DB >> 24266027

Metal-free nitro-carbocyclization of activated alkenes: a direct approach to synthesize oxindoles by cascade C-N and C-C bond formation.

Tao Shen1, Yizhi Yuan, Ning Jiao.   

Abstract

A novel and direct metal-free nitro-carbocyclization of activated alkenes leading to valuable nitro-containing oxindoles via cascade C-N and C-C bond formation has been developed. The mechanistic study indicates that the initial NO and NO2 radical addition and the following C-H functionalization processes are involved in this transformation.

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Year:  2013        PMID: 24266027     DOI: 10.1039/c3cc47336h

Source DB:  PubMed          Journal:  Chem Commun (Camb)        ISSN: 1359-7345            Impact factor:   6.222


  2 in total

1.  Site-selective and metal-free C-H nitration of biologically relevant N-heterocycles.

Authors:  Junghyea Moon; Hyun Ku Ji; Nayoung Ko; Harin Oh; Min Seo Park; Suho Kim; Prithwish Ghosh; Neeraj Kumar Mishra; In Su Kim
Journal:  Arch Pharm Res       Date:  2021-10-18       Impact factor: 4.946

2.  K2S2O8-mediated radical cyclisation of 2-alkynylthioanisoles or -selenoanisoles: a green and regioselective route to 3-nitrobenzothiophenes and benzoselenophenes.

Authors:  Shi-Chao Lu; Botao Wu; Shi-Peng Zhang; Ya-Ling Gong; Shu Xu
Journal:  RSC Adv       Date:  2020-05-19       Impact factor: 3.361

  2 in total

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