Literature DB >> 24265336

Recurrent symptomatic hypoglycaemia with pancytopenia as a delayed presentation of Sheehan's syndrome with complete recovery after hormone replacement.

Pramila Dharmshaktu1, Jayeeta Bhowmick, Danny Manglani, Dinesh Kumar Dhanwal.   

Abstract

A 38-year-old woman presented to our hospital emergency section in altered sensorium and with blood pressure of 80/60 mm Hg. She gave a history of recurrent episodes of loss of consciousness for 15-20 days, generalised body swelling and generalised weakness for the past 5-6 years. On further evaluation she was found to have severe hypoglycaemic episodes. In view of history of pregnancy and significant blood loss during surgery and long history of lethargy, asthaenia and generalised anasarca, the patient was evaluated for Sheehan's syndrome. Her serum cortisol levels were very low and she was found to have central hypothyroidism. MRI of the brain also revealed small sella turcica and small pituitary gland suggestive of hypopituitarism. The patient was started on high-concentration dextrose drips, steroids and thyroid hormone replacement. The patient showed a marked improvement within 1 week of treatment. And she was discharged with an advice to follow-up at our outpatient department.

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Mesh:

Year:  2013        PMID: 24265336      PMCID: PMC3841429          DOI: 10.1136/bcr-2013-009014

Source DB:  PubMed          Journal:  BMJ Case Rep        ISSN: 1757-790X


  14 in total

1.  Sheehan's syndrome associated with pancytopenia due to marrow aplasia; full recovery with hormone replacement therapy.

Authors:  M Ozdogan; G Yazicioglu; I Karadogan; C Cevikol; U Karayalcin; L Undar
Journal:  Int J Clin Pract       Date:  2004-05       Impact factor: 2.503

Review 2.  Sheehan's syndrome.

Authors:  Fahrettin Keleştimur
Journal:  Pituitary       Date:  2003       Impact factor: 4.107

3.  Pituitary failure from Sheehan's syndrome in the puerperium. Two case reports.

Authors:  A A Lakhdar; E H McLaren; N S Davda; E J McKay; P C Rubin
Journal:  Br J Obstet Gynaecol       Date:  1987-10

Review 4.  Sheehan's syndrome with pancytopenia--complete recovery after hormone replacement (case series with review).

Authors:  Bashir Ahmad Laway; Javid Rasool Bhat; Shahnaz Ahmad Mir; Raja Sultan Zaman Khan; Mohd Iqbal Lone; Abdul Hamid Zargar
Journal:  Ann Hematol       Date:  2009-08-21       Impact factor: 3.673

5.  A case report of Sheehan's syndrome with acute onset, hyponatremia and severe anemia.

Authors:  Salvatore Anfuso; Tito Silvio Patrelli; Emanuele Soncini; Paolo Chiodera; Giovanni Maria Fadda; Giovanni Battista Nardelli
Journal:  Acta Biomed       Date:  2009-04

Review 6.  Sheehan's syndrome.

Authors:  D M Roberts
Journal:  Am Fam Physician       Date:  1988-01       Impact factor: 3.292

7.  Case of complete recovery of pancytopenia after treatment of hypopituitarism.

Authors:  Dae-Young Kim; Jee Hyun Kim; Young Joo Park; Kyung Hae Jung; Hee Sun Chung; Soo Shin; Sung-Soo Yun; Seonyang Park; Byoung Kook Kim
Journal:  Ann Hematol       Date:  2003-11-26       Impact factor: 3.673

8.  Clinical and laboratory evaluation of 40 patients with Sheehan's syndrome.

Authors:  N Ozbey; S Inanc; F Aral; A Azezli; Y Orhan; E Sencer; S Molvalilar
Journal:  Isr J Med Sci       Date:  1994-11

9.  Pituitary autoimmunity in patients with Sheehan's syndrome.

Authors:  Ravinder Goswami; Narayana Kochupillai; Patricia A Crock; Abdul Jaleel; Nandita Gupta
Journal:  J Clin Endocrinol Metab       Date:  2002-09       Impact factor: 5.958

10.  Sheehan's Syndrome A Case Report and Literature Review.

Authors:  S Errarhay; I Kamaoui; C Bouchikhi; H Châara; H Bouguern; S Tizniti; A Melhouf; A Banani
Journal:  Libyan J Med       Date:  2009-06-01       Impact factor: 1.657

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  2 in total

Review 1.  Hormones and the bone marrow: panhypopituitarism and pancytopenia in a man with a pituitary adenoma.

Authors:  Dianna Lang; Jennifer S Mead; David B Sykes
Journal:  J Gen Intern Med       Date:  2015-05       Impact factor: 5.128

Review 2.  Sheehan's syndrome: new insights into an old disease.

Authors:  Halit Diri; Zuleyha Karaca; Fatih Tanriverdi; Kursad Unluhizarci; Fahrettin Kelestimur
Journal:  Endocrine       Date:  2015-09-01       Impact factor: 3.633

  2 in total

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