Literature DB >> 2426464

Genetic reassortants of lymphocytic choriomeningitis virus: unexpected disease and mechanism of pathogenesis.

Y Riviere, M B Oldstone.   

Abstract

Reassortant viruses of different strains of lymphocytic choriomeningitis viruses cause lethal disease after inoculation into neonatal BALB/c WEHI mice, but, in contrast, parental strains or reciprocal reassortants do not cause lethal disease. The disease is characterized by inhibition of growth and death. The pathogenic mechanism is the induction of interferon combined with higher virus titers and subsequent liver necrosis. The generation of lethal reassortants from nonlethal parent viruses likely has implications for understanding the outbreaks of unanticipated virulent disease within a viral family.

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Year:  1986        PMID： 2426464      PMCID： PMC253085     

Source DB:  PubMed          Journal:  J Virol        ISSN： 0022-538X            Impact factor:   5.103


  23 in total

1.  Lethality of interferon preparations for newborn mice.

Authors:  I Gresser; M G Tovey; C Maury; I Chouroulinkov
Journal:  Nature       Date:  1975-11-06       Impact factor: 49.962

Review 2.  MHC-restricted cytotoxic T cells: studies on the biological role of polymorphic major transplantation antigens determining T-cell restriction-specificity, function, and responsiveness.

Authors:  R M Zinkernagel; P C Doherty
Journal:  Adv Immunol       Date:  1979       Impact factor: 3.543

3.  Correlation of pathogenicity and gene constellation of influenza A viruses. II. Highly neurovirulent recombinants derived from non-neurovirulent or weakly neurovirulent parent virus strains.

Authors:  C Scholtissek; A Vallbracht; B Flehmig; R Rott
Journal:  Virology       Date:  1979-06       Impact factor: 3.616

4.  Recombination of influenza A strains with fowl plague virus can change pneumotropism for mice to a generalized infection with involvement of the central nervous system.

Authors:  A Vallbracht; C Scholtissek; B Flehmig; H J Gerth
Journal:  Virology       Date:  1980-12       Impact factor: 3.616

5.  Genetic reassortment of influenza A viruses in the intestinal tract of ducks.

Authors:  V S Hinshaw; W J Bean; R G Webster; G Sriram
Journal:  Virology       Date:  1980-04-30       Impact factor: 3.616

6.  Analyses of Patois group Bunyaviruses: evidence for naturally occurring recombinant Bunyaviruses and existence of immune precipitable and nonprecipitable nonvirion proteins induced in Burnyavirus-infected cells.

Authors:  H Ushijima; M Clerx-van Haaster; D H Bishop
Journal:  Virology       Date:  1981-04-30       Impact factor: 3.616

7.  Perturbation of differentiated functions during viral infection in vivo. II. Viral reassortants map growth hormone defect to the S RNA of the lymphocytic choriomeningitis virus genome.

Authors:  Y Riviere; R Ahmed; P Southern; M B Oldstone
Journal:  Virology       Date:  1985-04-15       Impact factor: 3.616

8.  Susceptibility of newborn mice with H-2k backgrounds to lymphocytic choriomeningitis virus infection.

Authors:  L B Doyle; M V Doyle; M B Oldstone
Journal:  Immunology       Date:  1980-08       Impact factor: 7.397

9.  Molecular basis of reovirus virulence. Role of the M2 gene.

Authors:  D H Rubin; B N Fields
Journal:  J Exp Med       Date:  1980-10-01       Impact factor: 14.307

10.  Severity of lymphocytic choriomeningitis virus disease in different strains of suckling mice correlates with increasing amounts of endogenous interferon.

Authors:  Y Rivière; I Gresser; J C Guillon; M T Bandu; P Ronco; L Morel-Maroger; P Verroust
Journal:  J Exp Med       Date:  1980-09-01       Impact factor: 14.307
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  20 in total

1.  The reovirus M1 gene, encoding a viral core protein, is associated with the myocarditic phenotype of a reovirus variant.

Authors:  B Sherry; B N Fields
Journal:  J Virol       Date:  1989-11       Impact factor: 5.103

2.  A live attenuated vaccine for Lassa fever made by reassortment of Lassa and Mopeia viruses.

Authors:  Igor S Lukashevich; Jean Patterson; Ricardo Carrion; Dmitry Moshkoff; Anysha Ticer; Juan Zapata; Kathleen Brasky; Robert Geiger; Gene B Hubbard; Joseph Bryant; Maria S Salvato
Journal:  J Virol       Date:  2005-11       Impact factor: 5.103

3.  Competitive selection in vivo by a cell for one variant over another: implications for RNA virus quasispecies in vivo.

Authors:  J Dockter; C F Evans; A Tishon; M B Oldstone
Journal:  J Virol       Date:  1996-03       Impact factor: 5.103

4.  Efficient virus extinction by combinations of a mutagen and antiviral inhibitors.

Authors:  N Pariente; S Sierra; P R Lowenstein; E Domingo
Journal:  J Virol       Date:  2001-10       Impact factor: 5.103

5.  CD4-deficient mice have reduced levels of memory cytotoxic T lymphocytes after immunization and show diminished resistance to subsequent virus challenge.

Authors:  M G von Herrath; M Yokoyama; J Dockter; M B Oldstone; J L Whitton
Journal:  J Virol       Date:  1996-02       Impact factor: 5.103

Review 6.  Lymphocytic choriomeningitis virus (LCMV) infection of macaques: a model for Lassa fever.

Authors:  Juan C Zapata; C David Pauza; Mahmoud M Djavani; Juan D Rodas; Dmitry Moshkoff; Joseph Bryant; Eugene Ateh; Cybele Garcia; Igor S Lukashevich; Maria S Salvato
Journal:  Antiviral Res       Date:  2011-07-27       Impact factor: 5.970

Review 7.  VaxCelerate II: rapid development of a self-assembling vaccine for Lassa fever.

Authors:  Pierre Leblanc; Leonard Moise; Cybelle Luza; Kanawat Chantaralawan; Lynchy Lezeau; Jianping Yuan; Mary Field; Daniel Richer; Christine Boyle; William D Martin; Jordan B Fishman; Eric A Berg; David Baker; Brandon Zeigler; Dale E Mais; William Taylor; Russell Coleman; H Shaw Warren; Jeffrey A Gelfand; Anne S De Groot; Timothy Brauns; Mark C Poznansky
Journal:  Hum Vaccin Immunother       Date:  2014       Impact factor: 3.452

8.  Genetic basis of viral persistence: single amino acid change in the viral glycoprotein affects ability of lymphocytic choriomeningitis virus to persist in adult mice.

Authors:  M Matloubian; T Somasundaram; S R Kolhekar; R Selvakumar; R Ahmed
Journal:  J Exp Med       Date:  1990-10-01       Impact factor: 14.307

Review 9.  Advanced vaccine candidates for Lassa fever.

Authors:  Igor S Lukashevich
Journal:  Viruses       Date:  2012-10-29       Impact factor: 5.048

10.  Thymic selection and adaptability of cytotoxic T lymphocyte responses in transgenic mice expressing a viral protein in the thymus.

Authors:  M G von Herrath; J Dockter; M Nerenberg; J E Gairin; M B Oldstone
Journal:  J Exp Med       Date:  1994-11-01       Impact factor: 14.307
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