Angelico Mendy1, Edgar R Vieira2, Ahmed N Albatineh3, Augustine K Nnadi4, Dana Lowry5, Janvier Gasana6. 1. Department of Epidemiology, College of Public Health, University of Iowa, Iowa City, Iowa. Electronic address: angelico-mendy@uiowa.edu. 2. Department of Physical Therapy, Florida International University, Miami, Florida. 3. Department of Biostatistics, Florida International University, Miami, Florida. 4. Department of Internal Medicine, Saint Joseph Hospital, Chicago, Illinois. 5. Department of Occupational and Environmental Health, College of Public Health, University of Iowa, Iowa City, Iowa. 6. South Florida Asthma Consortium, Fort Lauderdale, Florida.
Abstract
PURPOSE: Bone demineralization affects the skeletal system, including the temporal bone, which contains the cochlea and the vestibular labyrinth. However, research on the association of bone mineral density (BMD) with balance and hearing sensitivity is limited with conflicting results. Therefore, we examined the relationship in a population representative sample. METHODS: We analyzed 8863 participants to the National Health and Nutrition Examination Survey (1999-2004) aged 40 years and older. Total and head BMD were measured by dual energy x-ray absorptiometry. Balance was evaluated using the Romberg Test of Standing Balance on Firm and Compliant Support Surfaces condition 4, also indicative of vestibular dysfunction. Hearing condition was self-reported. The associations of total and head BMD with balance and hearing were assessed using multiple and multinomial logistic regressions adjusting for covariates. RESULTS: On multiple logistic regression, low total BMD was associated with balance impairment (odds ratio [OR], 2.21; 95% confidence interval [CI], 1.43-4.75), especially in older adults (≥65 years old; OR, 3.72; 95% CI, 1.07-12.85). In multinomial regression, low total BMD was associated with report of significant hearing impairment in older adults (OR, 5.30; 95% CI, 1.20-23.26). CONCLUSIONS: Low BMD is associated with balance and hearing impairments, especially in older adults.
PURPOSE: Bone demineralization affects the skeletal system, including the temporal bone, which contains the cochlea and the vestibular labyrinth. However, research on the association of bone mineral density (BMD) with balance and hearing sensitivity is limited with conflicting results. Therefore, we examined the relationship in a population representative sample. METHODS: We analyzed 8863 participants to the National Health and Nutrition Examination Survey (1999-2004) aged 40 years and older. Total and head BMD were measured by dual energy x-ray absorptiometry. Balance was evaluated using the Romberg Test of Standing Balance on Firm and Compliant Support Surfaces condition 4, also indicative of vestibular dysfunction. Hearing condition was self-reported. The associations of total and head BMD with balance and hearing were assessed using multiple and multinomial logistic regressions adjusting for covariates. RESULTS: On multiple logistic regression, low total BMD was associated with balance impairment (odds ratio [OR], 2.21; 95% confidence interval [CI], 1.43-4.75), especially in older adults (≥65 years old; OR, 3.72; 95% CI, 1.07-12.85). In multinomial regression, low total BMD was associated with report of significant hearing impairment in older adults (OR, 5.30; 95% CI, 1.20-23.26). CONCLUSIONS: Low BMD is associated with balance and hearing impairments, especially in older adults.
Authors: Robin T Bigelow; Yevgeniy R Semenov; Eric Anson; Sascha du Lac; Luigi Ferrucci; Yuri Agrawal Journal: J Assoc Res Otolaryngol Date: 2016-07-22