Literature DB >> 24261900

Acute phase Peyronie's disease management with traction device: a nonrandomized prospective controlled trial with ultrasound correlation.

Juan I Martínez-Salamanca1, Alejandra Egui, Ignacio Moncada, Javier Minaya, Claudio Martínez Ballesteros, Luis Del Portillo, Ignacio Sola, Joaquín Carballido.   

Abstract

INTRODUCTION: Outcome data of penile traction therapy (PTT) for the acute phase (AP) of Peyronie's disease (PD) have not been specifically studied. AIM: The aim of this study was to assess the effectiveness of a penile extender device for the treatment of patients with AP of PD.
METHODS: A total of 55 patients underwent PTT for 6 months and were compared with 41 patients with AP of PD who did not receive active treatment ("no intervention group" [NIG]). MAIN OUTCOMES MEASURES: Pre- and posttreatment variables included degree of curvature, penile length and girth, pain by 0-10 cm visual analog scale (VAS), erectile function (EF) domain of the International Index of Erectile Function questionnaire, Erection Hardness Scale, Sexual Encounter Profile 2 question, and penile sonographic evaluation (only patients in the intervention group).
RESULTS: The mean curvature decreased from 33° at baseline to 15° at 6 months and 13° at 9 months with a mean decrease 20° (P < 0.05) in the PTT group. VAS score for pain decreased from 5.5 to 2.5 after 6 months (P < 0.05). EF and erection hardness also improved significantly. The percentage of patients who were not able to achieve penetration decreased from 62% to 20% (P < 0.03). In the NIG, deformity increased significantly, stretched flaccid penile length decreased, VAS score for pain increased, and EF and erection hardness worsened. PTT was associated with the disappearance of sonographic plaques in 48% of patients. Furthermore, the need for surgery was reduced in 40% of patients who would otherwise have been candidates for surgery and simplified the complexity of the surgical procedure (from grafting to plication) in one out of every three patients.
CONCLUSIONS: PTT seems an effective treatment for the AP of PD in terms of pain reduction, penile curvature decrease, and improvement in sexual function.
© 2013 International Society for Sexual Medicine.

Entities:  

Keywords:  Erectile Dysfunction; Methods; Penile Induration; Peyronie's Disease; Therapy; Traction; Tunica Albuginea

Mesh:

Year:  2013        PMID: 24261900     DOI: 10.1111/jsm.12400

Source DB:  PubMed          Journal:  J Sex Med        ISSN: 1743-6095            Impact factor:   3.802


  17 in total

Review 1.  Nonsurgical treatment options in Peyronie's Disease: 2016 update.

Authors:  Raidh A Talib; Mohammed Abdulkareem Ibrahim; Önder Cangüven
Journal:  Turk J Urol       Date:  2016-12

Review 2.  Contemporary Review of Peyronie's Disease Treatment.

Authors:  Edward Capoccia; Laurence A Levine
Journal:  Curr Urol Rep       Date:  2018-05-17       Impact factor: 3.092

Review 3.  2013-2014 updates in Peyronie's disease management.

Authors:  Benjamin A Sherer; Krishnan Warrior; Laurence A Levine
Journal:  Curr Urol Rep       Date:  2014-12       Impact factor: 3.092

Review 4.  Experience in the use of collagenase clostridium histolyticum in the management of Peyronie's disease: current data and future prospects.

Authors:  María Alejandra Egui Rojo; Ignacio Moncada Iribarren; Joaquín Carballido Rodriguez; Juan Ignacio Martinez-Salamanca
Journal:  Ther Adv Urol       Date:  2014-10

Review 5.  Indications and characteristics of penile traction and vacuum erection devices.

Authors:  Abida Sultana; Peter Grice; Josip Vukina; Ian Pearce; Vaibhav Modgil
Journal:  Nat Rev Urol       Date:  2021-11-11       Impact factor: 14.432

Review 6.  --- ---Recent advances in managing Peyronie's disease.

Authors:  Oliver Kayes; Rauf Khadr
Journal:  F1000Res       Date:  2016-09-26

Review 7.  Penile traction therapy for Peyronie's disease-what's the evidence?

Authors:  Mustafa Faruk Usta; Tumay Ipekci
Journal:  Transl Androl Urol       Date:  2016-06

Review 8.  Lengthening strategies for Peyronie's disease.

Authors:  Christopher D Gaffney; Matthew J Pagano; Aaron C Weinberg; Alex C Small; Franklin E Kuehas; Paulo H Egydio; Robert J Valenzuela
Journal:  Transl Androl Urol       Date:  2016-06

9.  Efficacy and safety evaluation of pentoxifylline associated with other antioxidants in medical treatment of Peyronie's disease: a case-control study.

Authors:  Gianni Paulis; Davide Barletta; Paolo Turchi; Antonio Vitarelli; Giuseppe Dachille; Andrea Fabiani; Romano Gennaro
Journal:  Res Rep Urol       Date:  2015-12-31

Review 10.  Nonsurgical Interventions for Peyronie's Disease: Update as of 2016.

Authors:  Gregory A Joice; Arthur L Burnett
Journal:  World J Mens Health       Date:  2016-08-23       Impact factor: 5.400

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