OBJECTIVE: This article will review the multimodality imaging spectrum of medullary thyroid carcinoma (MTC) with an emphasis on anatomic and functional imaging. Recent advances in the molecular cytogenetics of this tumor and the impact on diagnosis, prognosis, and development of novel targeted therapy will be discussed. CONCLUSION: MTC is a neuroendocrine tumor with unique clinicopathologic and radiologic features compared with other thyroid malignancies. Imaging plays an important role in the optimal management of this malignancy.
OBJECTIVE: This article will review the multimodality imaging spectrum of medullary thyroid carcinoma (MTC) with an emphasis on anatomic and functional imaging. Recent advances in the molecular cytogenetics of this tumor and the impact on diagnosis, prognosis, and development of novel targeted therapy will be discussed. CONCLUSION: MTC is a neuroendocrine tumor with unique clinicopathologic and radiologic features compared with other thyroid malignancies. Imaging plays an important role in the optimal management of this malignancy.
Authors: Lilian Yuri Itaya Yamaga; Marcelo L Cunha; Guilherme C Campos Neto; Marcio R T Garcia; Ji H Yang; Cleber P Camacho; Jairo Wagner; Marcelo B G Funari Journal: Eur J Nucl Med Mol Imaging Date: 2017-04-20 Impact factor: 9.236