Literature DB >> 24257620

Assessing the susceptibility of transgenic mice overexpressing deer prion protein to bovine spongiform encephalopathy.

Christopher M Vickery1, Richard Lockey, Thomas M Holder, Leigh Thorne, Katy E Beck, Christina Wilson, Margaret Denyer, John Sheehan, Sarah Marsh, Paul R Webb, Ian Dexter, Angela Norman, Emma Popescu, Amanda Schneider, Paul Holden, Peter C Griffiths, Jane M Plater, Mark P Dagleish, Stuart Martin, Glenn C Telling, Marion M Simmons, John Spiropoulos.   

Abstract

Several transgenic mouse models have been developed which facilitate the transmission of chronic wasting disease (CWD) of cervids and allow prion strain discrimination. The present study was designed to assess the susceptibility of the prototypic mouse line, Tg(CerPrP)1536(+/-), to bovine spongiform encephalopathy (BSE) prions, which have the ability to overcome species barriers. Tg(CerPrP)1536(+/-) mice challenged with red deer-adapted BSE resulted in 90% to 100% attack rates, and BSE from cattle failed to transmit, indicating agent adaptation in the deer.

Entities:  

Mesh：

Substances：

Year:  2013        PMID： 24257620      PMCID： PMC3911610          DOI： 10.1128/JVI.02762-13

Source DB:  PubMed          Journal:  J Virol        ISSN： 0022-538X            Impact factor:   5.103


  29 in total

1.  Ovine PrP genotype is linked with lesion profile and immunohistochemistry patterns after primary transmission of classical scrapie to wild-type mice.

Authors:  Katy E Beck; Rosemary E Sallis; Richard Lockey; Marion M Simmons; John Spiropoulos
Journal:  J Neuropathol Exp Neurol       Date:  2010-05       Impact factor: 3.685

2.  Identification of new quantitative trait Loci (other than the PRNP gene) modulating the scrapie incubation period in sheep.

Authors:  C R Moreno; G M Cosseddu; L Schibler; A Roig; K Moazami-Goudarzi; O Andreoletti; F Eychenne; D Lajous; F Schelcher; E P Cribiu; P Laurent; D Vaiman; J M Elsen
Journal:  Genetics       Date:  2008-05       Impact factor: 4.562

3.  Detection of chronic wasting disease prions in salivary, urinary, and intestinal tissues of deer: potential mechanisms of prion shedding and transmission.

Authors:  Nicholas J Haley; Candace K Mathiason; Scott Carver; Mark Zabel; Glenn C Telling; Edward A Hoover
Journal:  J Virol       Date:  2011-04-27       Impact factor: 5.103

4.  Minor oral lesions facilitate transmission of chronic wasting disease.

Authors:  Nathaniel D Denkers; Glenn C Telling; Edward A Hoover
Journal:  J Virol       Date:  2010-11-17       Impact factor: 5.103

5.  Transmission of scrapie and sheep-passaged bovine spongiform encephalopathy prions to transgenic mice expressing elk prion protein.

Authors:  Gültekin Tamgüney; Michael W Miller; Kurt Giles; Azucena Lemus; David V Glidden; Stephen J DeArmond; Stanley B Prusiner
Journal:  J Gen Virol       Date:  2009-03-04       Impact factor: 3.891

6.  The elk PRNP codon 132 polymorphism controls cervid and scrapie prion propagation.

Authors:  Kristi M Green; Shawn R Browning; Tanya S Seward; Jean E Jewell; Dana L Ross; Michael A Green; Elizabeth S Williams; Edward A Hoover; Glenn C Telling
Journal:  J Gen Virol       Date:  2008-02       Impact factor: 3.891

7.  H-type bovine spongiform encephalopathy: complex molecular features and similarities with human prion diseases.

Authors:  Anne-Gaëlle Biacabe; Jorg G Jacobs; Anna Bencsik; Jan P M Langeveld; Thierry G M Baron
Journal:  Prion       Date:  2007-01-11       Impact factor: 3.931

Review 8.  Occurrence, transmission, and zoonotic potential of chronic wasting disease.

Authors:  Samuel E Saunders; Shannon L Bartelt-Hunt; Jason C Bartz
Journal:  Emerg Infect Dis       Date:  2012-03       Impact factor: 6.883

9.  Aerosol and nasal transmission of chronic wasting disease in cervidized mice.

Authors:  Nathaniel D Denkers; Davis M Seelig; Glenn C Telling; Edward A Hoover
Journal:  J Gen Virol       Date:  2010-02-17       Impact factor: 3.891

10.  Detection of CWD prions in urine and saliva of deer by transgenic mouse bioassay.

Authors:  Nicholas J Haley; Davis M Seelig; Mark D Zabel; Glenn C Telling; Edward A Hoover
Journal:  PLoS One       Date:  2009-03-18       Impact factor: 3.240
View more
  7 in total

Review 1.  Molecular Mechanisms of Chronic Wasting Disease Prion Propagation.

Authors:  Julie A Moreno; Glenn C Telling
Journal:  Cold Spring Harb Perspect Med       Date:  2018-06-01       Impact factor: 6.915

2.  Prion replication without host adaptation during interspecies transmissions.

Authors:  Jifeng Bian; Vadim Khaychuk; Rachel C Angers; Natalia Fernández-Borges; Enric Vidal; Crystal Meyerett-Reid; Sehun Kim; Carla L Calvi; Jason C Bartz; Edward A Hoover; Umberto Agrimi; Jürgen A Richt; Joaquín Castilla; Glenn C Telling
Journal:  Proc Natl Acad Sci U S A       Date:  2017-01-17       Impact factor: 11.205

Review 3.  Chronic Wasting Disease (CWD) in Cervids and the Consequences of a Mutable Protein Conformation.

Authors:  Christopher J Silva
Journal:  ACS Omega       Date:  2022-04-04

4.  Susceptibility of European red deer (Cervus elaphus elaphus) to alimentary challenge with bovine spongiform encephalopathy.

Authors:  Mark P Dagleish; Stuart Martin; Philip Steele; Jeanie Finlayson; Samantha L Eaton; Sílvia Sisó; Paula Stewart; Natalia Fernández-Borges; Scott Hamilton; Yvonne Pang; Francesca Chianini; Hugh W Reid; Wilfred Goldmann; Lorenzo González; Joaquín Castilla; Martin Jeffrey
Journal:  PLoS One       Date:  2015-01-23       Impact factor: 3.240

5.  Complex folding and misfolding effects of deer-specific amino acid substitutions in the β2-α2 loop of murine prion protein.

Authors:  Sonya Agarwal; Kristina Döring; Leszek A Gierusz; Pooja Iyer; Fiona M Lane; James F Graham; Wilfred Goldmann; Teresa J T Pinheiro; Andrew C Gill
Journal:  Sci Rep       Date:  2015-10-22       Impact factor: 4.379

6.  L-BSE experimentally transmitted to sheep presents as a unique disease phenotype.

Authors:  Marion M Simmons; Melanie J Chaplin; Timm Konold; Cristina Casalone; Katy E Beck; Leigh Thorne; Sharon Everitt; Tobias Floyd; Derek Clifford; John Spiropoulos
Journal:  Vet Res       Date:  2016-11-08       Impact factor: 3.683

Review 7.  Gene-Edited Cell Models to Study Chronic Wasting Disease.

Authors:  Simrika Thapa; Cristobal Marrero Winkens; Waqas Tahir; Maria I Arifin; Sabine Gilch; Hermann M Schatzl
Journal:  Viruses       Date:  2022-03-15       Impact factor: 5.048
  7 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.