Literature DB >> 24257482

Evaluation of neck pain with (18)F-NaF PET/CT.

Tiernan J D Byrnes1, Wanying Xie, Omar Al-Mukhailed, Anthony D'Sa, Fuad Novruzov, Adrian T H Casey, Charles House, Jamshed B Bomanji.   

Abstract

AIM: (18)F-Sodium fluoride ((18)F-NaF) PET/computed tomography (CT) has improved spatial resolution in the cervical spine compared with single photon emission computed tomography/CT techniques using traditional tracers. Limited data are available, however, on its effectiveness in the management of the symptomatic cervical spine, and the aim of this study was therefore to elucidate this issue. PATIENTS AND METHODS: A retrospective study was carried out between April 2011 and April 2012. Across this period, 66 patients were referred to the department for the assessment of neck pain, of whom 58 were included in the study. (18)F-NaF was used as the tracer and images were acquired on an integrated PET/CT scanner. All studies were evaluated by either consultant nuclear medicine physicians or by a radiologist. Two consultant neurosurgeons correlated the imaging reports with the clinical data from the patient notes to give an overall impression as to how beneficial the test had been with regard to patient management.
RESULTS: In 49/58 (84.5%) cases, the (18)F-NaF PET/CT report was thought to have been clinically useful in patient management. In 9/58 (15.5%) cases, the report was thought not to have been clinically beneficial, generally because of high background vertebral uptake of (18)F-fluoride secondary to degenerative disease.
CONCLUSION: As our experience with (18)F-NaF PET/CT broadens, we believe that it will become an increasingly important tool in the evaluation and management of the symptomatic cervical spine.

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Year:  2014        PMID: 24257482     DOI: 10.1097/MNM.0000000000000044

Source DB:  PubMed          Journal:  Nucl Med Commun        ISSN: 0143-3636            Impact factor:   1.690


  5 in total

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4.  Pseudarthrosis after lumbar spinal fusion: the role of ¹⁸F-fluoride PET/CT.

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5.  Inhibition of galectin-3 ameliorates the consequences of cardiac lipotoxicity in a rat model of diet-induced obesity.

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Journal:  Dis Model Mech       Date:  2018-02-05       Impact factor: 5.758

  5 in total

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