Literature DB >> 24257260

[Crystalline keratopathy due to kappa chains in a monoclonal gammopathy].

J C Mesa-Gutiérrez1, A Rouras-López, V Amías-Lamana, J Hoyos-Chacón, I Cabiró-Badimón, J Porta-Monnet.   

Abstract

CASE REPORT: The following case shows corneal crystal formation in a patient in whom thee systemic work-up led to the diagnosis of a monoclonal gammopathy with increased monoclonal immunoglobulin G (IgG). We present the corneal signs and subsequent haematological investigations undertaken to establish this important association. DISCUSSION: Systemic work-up of a patient with corneal deposits showed a monoclonal gammopathy with increased monoclonal immunoglobulin (IgG-type kappa). Corneal crystals, a rare, but significant, clinical finding, may be the initial presentation in a patient with monoclonal gammopathy.
Copyright © 2012 Sociedad Española de Oftalmología. Published by Elsevier Espana. All rights reserved.

Entities:  

Keywords:  Cadenas ligeras kappa; Corneal crystals; Cristales corneales; Gammapatía monoclonal; Immunoglobulin G; Inmunoglobulina G; Kappa light chains; Monoclonal gammopathy

Mesh:

Substances:

Year:  2012        PMID: 24257260     DOI: 10.1016/j.oftal.2012.06.019

Source DB:  PubMed          Journal:  Arch Soc Esp Oftalmol        ISSN: 0365-6691


  2 in total

1.  Recurrence of paraproteinemic crystalline keratopathy after corneal transplantation: A case of monoclonal gammopathy of ocular significance.

Authors:  Siamak Nobacht; Benno Kusters; Myrte B Breukink; Gerard A Rongen; Johannes R M Cruysberg
Journal:  Am J Ophthalmol Case Rep       Date:  2020-07-02

Review 2.  Paraproteinemic keratopathy in monoclonal gammopathy of undetermined significance treated with primary keratoprosthesis: Case report, histopathologic findings, and world literature review.

Authors:  Homer H Chiang; Rebekah S Wieland; Thomas S Rogers; Pamela C Gibson; George Atweh; Gregory McCormick
Journal:  Medicine (Baltimore)       Date:  2017-12       Impact factor: 1.817

  2 in total

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