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Literature DB >> 24254827

Response of hepatic metallothionein to iron administration : Lack of correlation with serum corticosterone.

Abstract

Female broiler chicks receiving an ip injection of Fe (10 mg/kg bw) were found to have a greatly increased level of hepatic metallothionein. The increase in metallothionein was not correlated with changes in serum corticosterone. Attempts to vary serum corticosterone levels by feeding metyrapone, an 11-β steroid hydroxylase inhibitor, were unsuccessful.

Entities: Chemical

Year: 1987 PMID： 24254827 DOI： 10.1007/BF02795692

Source DB: PubMed Journal: Biol Trace Elem Res ISSN： 0163-4984 Impact factor: 3.738

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References

11 in total

1. Some studies of the protein-binding of steroids and their application to the routine micro and ultramicro measurement of various steroids in body fluids by competitive protein-binding radioassay.

Authors: B E Murphy
Journal: J Clin Endocrinol Metab Date: 1967-07 Impact factor: 5.958

2. Equine hepatic and renal metallothioneins. Purification, molecular weight, amino acid composition, and metal content.

Authors: J H Kägi; S R Himmelhoch; P D Whanger; J L Bethune; B L Vallee
Journal: J Biol Chem Date: 1974-06-10 Impact factor: 5.157

3. Cell-mediated immunity in Marek's disease virus-infected chickens genetically selected for high and low concentrations of plasma corticosterone.

Authors: D L Thompson; K D Elgert; W B Gross; P B Siegel
Journal: Am J Vet Res Date: 1980-01 Impact factor: 1.156

4. Evaluation of the Cd/hemoglobin affinity assay for the rapid determination of metallothionein in biological tissues.

Authors: D L Eaton; B F Toal
Journal: Toxicol Appl Pharmacol Date: 1982-10 Impact factor: 4.219

5. Regulation of liver metallothionein and plasma zinc by the glucocorticoid dexamethasone.

Authors: K R Etzel; S G Shapiro; R J Cousins
Journal: Biochem Biophys Res Commun Date: 1979-08-28 Impact factor: 3.575

6. Splenic leukocytes from chickens injected with Salmonella pullorum antigen stimulate production of corticosteroids by isolated adrenal cells.

Authors: H S Siegel; N R Gould; J W Latimer
Journal: Proc Soc Exp Biol Med Date: 1985-04

Response of hepatic metallothionein to iron administration : Lack of correlation with serum corticosterone.

1. Some studies of the protein-binding of steroids and their application to the routine micro and ultramicro measurement of various steroids in body fluids by competitive protein-binding radioassay.

2. Equine hepatic and renal metallothioneins. Purification, molecular weight, amino acid composition, and metal content.

3. Cell-mediated immunity in Marek's disease virus-infected chickens genetically selected for high and low concentrations of plasma corticosterone.

4. Evaluation of the Cd/hemoglobin affinity assay for the rapid determination of metallothionein in biological tissues.

5. Regulation of liver metallothionein and plasma zinc by the glucocorticoid dexamethasone.

6. Splenic leukocytes from chickens injected with Salmonella pullorum antigen stimulate production of corticosteroids by isolated adrenal cells.

7. The tissue-specific accumulation of hepatic zinc metallothionein following parenteral iron loading.

8. Biological function of metallothionein. V. Its induction in rats by various stresses.

9. Involvement of hepatic metallothioneins in hypozincemia associated with bacterial infection.

10. Induction of metallothionein by adrenocortical steroids.