Ignasi Garcia-Olivé1, Jose Sanz-Santos2, Carmen Centeno3, Felipe Andreo4, Aida Muñoz-Ferrer3, Pere Serra3, Jaume Sampere5, Josep Maria Michavila5, Jordi Muchart5, Juan Ruiz Manzano6. 1. Respiratory Service, Hospital Universitari Germans Trias i Pujol, Carretera del Canyet sn, 08916, Badalona, Barcelona; Fundació Institut d'Investigació en Ciències de la Salut Germans Trias i Pujol, Badalona, Barcelona; CibeRes-Ciber de Enfermedades Respiratorias, Bunyola, Bunyola, Mallorca. Electronic address: ignasi.g.olive@gmail.com. 2. Respiratory Service, Hospital Universitari Germans Trias i Pujol, Carretera del Canyet sn, 08916, Badalona, Barcelona; Fundació Institut d'Investigació en Ciències de la Salut Germans Trias i Pujol, Badalona, Barcelona. 3. Respiratory Service, Hospital Universitari Germans Trias i Pujol, Carretera del Canyet sn, 08916, Badalona, Barcelona. 4. Respiratory Service, Hospital Universitari Germans Trias i Pujol, Carretera del Canyet sn, 08916, Badalona, Barcelona; Fundació Institut d'Investigació en Ciències de la Salut Germans Trias i Pujol, Badalona, Barcelona; CibeRes-Ciber de Enfermedades Respiratorias, Bunyola, Bunyola, Mallorca. 5. Department of Radiology, Hospital Universitari Germans Trias i Pujol, Carretera del Canyet sn, 08916, Badalona, Barcelona. 6. Respiratory Service, Hospital Universitari Germans Trias i Pujol, Carretera del Canyet sn, 08916, Badalona, Barcelona; Fundació Institut d'Investigació en Ciències de la Salut Germans Trias i Pujol, Badalona, Barcelona; CibeRes-Ciber de Enfermedades Respiratorias, Bunyola, Bunyola, Mallorca; Department of Medicine, Universitat Autònoma de Barcelona, Bellaterra, Spain.
Abstract
PURPOSE: To describe experience with bronchial artery embolization (BAE) in a cohort of patients with cancer. MATERIALS AND METHODS: All consecutive patients with cancer and at least one episode of hemoptysis that required BAE during a 14-year period were included in this observational retrospective review. The endpoints of the study were immediate success, recurrence of hemoptysis, mortality resulting from hemoptysis, and all-cause mortality. RESULTS: Immediate control of bleeding was achieved in 31 of 40 patients (77.5%). Recurrence requiring BAE occurred in eight patients (20%). Cumulative hemoptysis control rate was 0.90 (95% confidence interval [CI], 0.80-1.0) at 1 month and 0.65 (95% CI, 0.44-0.86) at 6 months. Probability of survival was 0.75 (95% CI, 0.62-0.88) at 1 month, 0.42 (95% CI, 0.27-0.57) at 6 months, 0.36 (95% CI, 0.21-0.51) at 12 months, and 0.08 (95% CI, 0.0-0.18) at 3 years. CONCLUSIONS: BAE is an effective and safe technique in the treatment of hemoptysis in patients with cancer. Nevertheless, mortality resulting from hemoptysis and recurrence rate are high among these patients secondary to progression of the underlying disease.
PURPOSE: To describe experience with bronchial artery embolization (BAE) in a cohort of patients with cancer. MATERIALS AND METHODS: All consecutive patients with cancer and at least one episode of hemoptysis that required BAE during a 14-year period were included in this observational retrospective review. The endpoints of the study were immediate success, recurrence of hemoptysis, mortality resulting from hemoptysis, and all-cause mortality. RESULTS: Immediate control of bleeding was achieved in 31 of 40 patients (77.5%). Recurrence requiring BAE occurred in eight patients (20%). Cumulative hemoptysis control rate was 0.90 (95% confidence interval [CI], 0.80-1.0) at 1 month and 0.65 (95% CI, 0.44-0.86) at 6 months. Probability of survival was 0.75 (95% CI, 0.62-0.88) at 1 month, 0.42 (95% CI, 0.27-0.57) at 6 months, 0.36 (95% CI, 0.21-0.51) at 12 months, and 0.08 (95% CI, 0.0-0.18) at 3 years. CONCLUSIONS:BAE is an effective and safe technique in the treatment of hemoptysis in patients with cancer. Nevertheless, mortality resulting from hemoptysis and recurrence rate are high among these patients secondary to progression of the underlying disease.
Authors: Amar S Mehta; Osman Ahmed; Danial Jilani; Steve Zangan; Jonathan Lorenz; Brian Funaki; Thuong Van Ha; Rakesh Navuluri Journal: J Thorac Dis Date: 2015-08 Impact factor: 2.895