Literature DB >> 24250916

Clinical and MRI manifestations of nitrous oxide induced vitamin B12 deficiency: A case report.

Anahid Safari1, Farhad Emadi, Elham Jamali, Afshin Borhani-Haghighi.   

Abstract

A 50 year-old man was referred with history of acute ataxia and lower extremity paresthesia 10 days after general anesthesia with nitrous oxide. Cervical MRI showed long hypersignal lesion in posterior segment of the cord. Blood analysis revealed vitamin B12 deficiency. Nitrous oxide-induced myelopathy should be considered in patients who develop acute neurological manifestation after general anesthesia. It is recommended for physicians to think about symptoms and signs of B12 deficiency when evaluating patients in postoperative visits.

Entities:  

Keywords:  Ataxia; General Anesthesia; Nitrous Oxide; Spinal Cord; Vitamin B12 Deficiency

Year:  2013        PMID: 24250916      PMCID: PMC3829298     

Source DB:  PubMed          Journal:  Iran J Neurol        ISSN: 2008-384X


  8 in total

Review 1.  Current concepts in the diagnosis of cobalamin deficiency.

Authors:  R Green; L J Kinsella
Journal:  Neurology       Date:  1995-08       Impact factor: 9.910

2.  MRI in vitamin B12 deficiency myelopathy.

Authors:  E R Locatelli; R Laureno; P Ballard; A S Mark
Journal:  Can J Neurol Sci       Date:  1999-02       Impact factor: 2.104

3.  Myelopathy caused by nitrous oxide toxicity.

Authors:  P J Pema; H A Horak; R H Wyatt
Journal:  AJNR Am J Neuroradiol       Date:  1998-05       Impact factor: 3.825

Review 4.  Neurologic degeneration associated with nitrous oxide anesthesia in patients with vitamin B12 deficiency.

Authors:  T S Flippo; W D Holder
Journal:  Arch Surg       Date:  1993-12

5.  Reversible myelopathy with vitamin B12 deficiency.

Authors:  M G Senol; G Sonmez; F Ozdag; M Saracoglu
Journal:  Singapore Med J       Date:  2008-11       Impact factor: 1.858

Review 6.  Myelotoxic, neurotoxic and reproductive adverse effects of nitrous oxide.

Authors:  R T Louis-Ferdinand
Journal:  Adverse Drug React Toxicol Rev       Date:  1994

7.  High prevalence of cobalamin deficiency in elderly outpatients.

Authors:  L C Pennypacker; R H Allen; J P Kelly; L M Matthews; J Grigsby; K Kaye; J Lindenbaum; S P Stabler
Journal:  J Am Geriatr Soc       Date:  1992-12       Impact factor: 5.562

8.  Sub-acute combined degeneration with an initially normal level of vitamin B12: a case report.

Authors:  Fadi Makdsi; Tareck Kadrie
Journal:  Cases J       Date:  2009-08-05
  8 in total
  2 in total

1.  Correlation between serum vitamin B12 level and peripheral neuropathy in atrophic gastritis.

Authors:  Guo-Tao Yang; Hong-Ying Zhao; Yu Kong; Ning-Ning Sun; Ai-Qin Dong
Journal:  World J Gastroenterol       Date:  2018-03-28       Impact factor: 5.742

2.  The neurotoxicity of nitrous oxide: the facts and "putative" mechanisms.

Authors:  Sinead Savage; Daqing Ma
Journal:  Brain Sci       Date:  2014-01-28
  2 in total

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