L Sikiru1, G C Okoye. 1. Department of Biomedical Technology, School of Health Technology, Federal University of Technology, Owerri, Nigeria.
Abstract
BACKGROUND:Pulse pressure (PP), might be a stronger determinants of cardiovascular risk. OBJECTIVE: To investigate the effect of interval training program on PP in subjects with hypertension. METHODS:Two hundred and forty five male patients with mild to moderate (Systolic Blood Pressure [SBP] between 140-179 & Diastolic Blood Pressure [DBP] between 90-109 mmHg) essential hypertension were age-matched and grouped into exercise and control groups. The exercise (work: rest ratio of 1:1) groups involved in an 8-weeks interval training programs of between 45-60 minutes, at intensities of 60-79% of HR max (maximum heart rate), while the control group remained sedentary during this period. SBP, DBP, VO2max and PP were assessed. RESULTS: Findings of the study revealed significant correlation between PP and blood pressure; correlation of PP with SBP was much stronger (95% variance). Also, there was significant effect of the exercise training program on SBP, DBP and PP. Changes in VO2max also negatively correlated with changes in PP (r= -.285) at p<0.05. CONCLUSION:Moderate intensity interval training programs is effective in the non-pharmacological management of hypertension and may prevent cardiovascular event through the down regulation of PP in hypertension.
RCT Entities:
BACKGROUND: Pulse pressure (PP), might be a stronger determinants of cardiovascular risk. OBJECTIVE: To investigate the effect of interval training program on PP in subjects with hypertension. METHODS: Two hundred and forty five male patients with mild to moderate (Systolic Blood Pressure [SBP] between 140-179 & Diastolic Blood Pressure [DBP] between 90-109 mmHg) essential hypertension were age-matched and grouped into exercise and control groups. The exercise (work: rest ratio of 1:1) groups involved in an 8-weeks interval training programs of between 45-60 minutes, at intensities of 60-79% of HR max (maximum heart rate), while the control group remained sedentary during this period. SBP, DBP, VO2max and PP were assessed. RESULTS: Findings of the study revealed significant correlation between PP and blood pressure; correlation of PP with SBP was much stronger (95% variance). Also, there was significant effect of the exercise training program on SBP, DBP and PP. Changes in VO2max also negatively correlated with changes in PP (r= -.285) at p<0.05. CONCLUSION: Moderate intensity interval training programs is effective in the non-pharmacological management of hypertension and may prevent cardiovascular event through the down regulation of PP in hypertension.
Authors: A R Dyer; J Stamler; R B Shekelle; J A Schoenberger; R Stamler; S Shekelle; P Collette; D M Berkson; O Paul; M H Lepper; H A Lindberg Journal: J Chronic Dis Date: 1982
Authors: Adrian Wong; Bonnie Yin Ka Lam; Margaret Kit Yi Mak; Linda Chiu Wa Lam; Lisa Wing Chi Au; Brian Ka Fung Yiu; Chun Wong; Hor Yee Tong; Sin Ki Yeung; Winnie Chiu Wing Chu; Lin Shi; Thomas Wai Hong Leung; Yannie Oi Yan Soo; Alexander Yuk Lun Lau; Bonaventure Yiu Ming Ip; Timothy Chi Yui Kwok; Ho Ko; Vincent Chung Tong Mok Journal: Alzheimers Dement (N Y) Date: 2021-12-31