BACKGROUND: Giant intracranial aneurysms are rare and heterogeneous lesions with complex vascular anatomy. The aim of this retrospective study was to provide a comprehensive description of the anatomical features of giant aneurysms. METHODS: We identified 125 patients with 129 giant aneurysms (≥ 25 mm) who were treated between 1987 and 2007 at the Department of Neurosurgery of Helsinki University Central Hospital (HUCH). All the imaging studies and medical records were reviewed for relevant information. RESULTS: The distribution of the giant aneurysms among regions was as follows: internal carotid artery (ICA) 39%, middle cerebral artery (MCA) 32%, vertebrobasilar and posterior cerebral artery (VB-PCA) region 25%, and anterior cerebral artery (ACA) including the anterior communicating artery 5%. The cavernous ICA segment (n = 21, 16%) and the MCA bifurcation (n = 25, 19%) were the most frequent specific locations. Half (n = 11) of all fusiform aneurysms were found in the VB-PCA region. As many as 41 % of the giant MCA aneurysms were ruptured. Major anatomic variations were found in three (2%) and multiple giant aneurysms in three (2%) patients. Wall calcification was noted in 24% and intraluminal thrombosis in 33% of ruptured giant aneurysms (n = 42). CONCLUSIONS: The majority of giant aneurysms are located in the ICA and MCA regions, while the ACA region is an exceptional site. The MCA region is the most common site for ruptured giant aneurysms. Associated anatomic variations and the multiplicity of giant aneurysms are a rare finding.
BACKGROUND: Giant intracranial aneurysms are rare and heterogeneous lesions with complex vascular anatomy. The aim of this retrospective study was to provide a comprehensive description of the anatomical features of giant aneurysms. METHODS: We identified 125 patients with 129 giant aneurysms (≥ 25 mm) who were treated between 1987 and 2007 at the Department of Neurosurgery of Helsinki University Central Hospital (HUCH). All the imaging studies and medical records were reviewed for relevant information. RESULTS: The distribution of the giant aneurysms among regions was as follows: internal carotid artery (ICA) 39%, middle cerebral artery (MCA) 32%, vertebrobasilar and posterior cerebral artery (VB-PCA) region 25%, and anterior cerebral artery (ACA) including the anterior communicating artery 5%. The cavernous ICA segment (n = 21, 16%) and the MCA bifurcation (n = 25, 19%) were the most frequent specific locations. Half (n = 11) of all fusiform aneurysms were found in the VB-PCA region. As many as 41 % of the giant MCA aneurysms were ruptured. Major anatomic variations were found in three (2%) and multiple giant aneurysms in three (2%) patients. Wall calcification was noted in 24% and intraluminal thrombosis in 33% of ruptured giant aneurysms (n = 42). CONCLUSIONS: The majority of giant aneurysms are located in the ICA and MCA regions, while the ACA region is an exceptional site. The MCA region is the most common site for ruptured giant aneurysms. Associated anatomic variations and the multiplicity of giant aneurysms are a rare finding.
Authors: Alba Scerrati; Giovanni Sabatino; Giuseppe Maria Della Pepa; Alessio Albanese; Enrico Marchese; Alfredo Puca; Alessandro Olivi; Carmelo Lucio Sturiale Journal: Neurosurg Rev Date: 2018-05-22 Impact factor: 3.042
Authors: Lei Huang; Wenjie Cao; Liang Ge; Gang Lu; Jun Wan; Lei Zhang; Weijin Gu; Xiaolong Zhang; Daoying Geng Journal: Int J Clin Exp Med Date: 2015-05-15
Authors: Mehdi Chihi; Ramazan Jabbarli; Oliver Gembruch; Sarah Teuber-Hanselmann; Marvin Darkwah Oppong; Daniela Pierscianek; Alexander Radbruch; Martin Glas; Mark Stettner; Ulrich Sure Journal: BMC Neurol Date: 2019-11-23 Impact factor: 2.474
Authors: Lars Wessels; Lucius Samo Fekonja; Johannes Achberger; Julius Dengler; Marcus Czabanka; Nils Hecht; Ulf Schneider; Dimitri Tkatschenko; Karl-Michael Schebesch; Nils Ole Schmidt; Dorothee Mielke; Henning Hosch; Oliver Ganslandt; Alexander Gräwe; Bujung Hong; Jan Walter; Erdem Güresir; Philippe Bijlenga; Julien Haemmerli; Nicolai Maldaner; Serge Marbacher; Ville Nurminen; Hynek Zitek; Ruben Dammers; Naoki Kato; Italo Linfante; Maria-Teresa Pedro; Karsten Wrede; Wei-Te Wang; Maria Wostrack; Peter Vajkoczy Journal: Acta Neurochir (Wien) Date: 2020-09-15 Impact factor: 2.216