Literature DB >> 24247207

Quantitative psychomotor dysfunction in schizophrenia: a loss of drive, impaired movement execution or both?

Lise Docx1, Bernard Sabbe, Pieter Provinciael, Niel Merckx, Manuel Morrens.   

Abstract

AIMS: The aim of the present study was to investigate the predictive value of qualitative psychomotor performance levels and subaspects of the negative syndrome for quantitative motor activity levels in patients with schizophrenia.
METHODS: Twenty-seven stabilized patients with schizophrenia and 22 age- and sex-matched healthy controls were included in the study. An extensive battery of psychomotor performance tests (Finger Tapping Test, Purdue Pegboard Test, Line Copying Test, Neurological Evaluation Scale, Salpêtrière Retardation Rating Scale), clinical rating scales (Positive and Negative Syndrome Scale) and 24-hour actigraphy were administered to all participants.
RESULTS: Correlational analyses showed that motor activity levels were associated with avolition as well as clinically assessed psychomotor slowing. However, in a regression model, only avolition was found to be a significant predictor for motor activity levels in patients with schizophrenia; none of the psychomotor performance tests nor the severity of emotional expressivity deficits contributed to the model.
CONCLUSION: Qualitative and quantitative psychomotor deficits seem to be independent phenomena in stabilized patients with schizophrenia. The diminishing in motor activity in patients with schizophrenia is related to a loss of drive and not to problems in the quality of movement execution.
© 2013 S. Karger AG, Basel.

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Year:  2013        PMID: 24247207     DOI: 10.1159/000355293

Source DB:  PubMed          Journal:  Neuropsychobiology        ISSN: 0302-282X            Impact factor:   2.328


  15 in total

1.  Actigraphy studies and clinical and biobehavioural correlates in schizophrenia: a systematic review.

Authors:  Zi Ying Wee; Samantha Wei Lee Yong; Qian Hui Chew; Cuntai Guan; Tih Shih Lee; Kang Sim
Journal:  J Neural Transm (Vienna)       Date:  2019-03-19       Impact factor: 3.575

2.  Taking Personalized Medicine Seriously: Biomarker Approaches in Phase IIb/III Studies in Major Depression and Schizophrenia.

Authors:  Harald Murck; Thomas Laughren; Femke Lamers; Rosalind Picard; Sebastian Walther; Donald Goff; Stephen Sainati
Journal:  Innov Clin Neurosci       Date:  2015 Mar-Apr

3.  Aberrant Hyperconnectivity in the Motor System at Rest Is Linked to Motor Abnormalities in Schizophrenia Spectrum Disorders.

Authors:  Sebastian Walther; Katharina Stegmayer; Andrea Federspiel; Stephan Bohlhalter; Roland Wiest; Petra V Viher
Journal:  Schizophr Bull       Date:  2017-09-01       Impact factor: 9.306

4.  Rigidity in Motor Behavior and Brain Functioning in Patients With Schizophrenia and High Levels of Apathy.

Authors:  Michelle N Servaas; Claire Kos; Nicolás Gravel; Remco J Renken; Jan-Bernard C Marsman; Marie-José van Tol; André Aleman
Journal:  Schizophr Bull       Date:  2019-04-25       Impact factor: 9.306

5.  Low physical activity is associated with two hypokinetic motor abnormalities in psychosis.

Authors:  Sebastian Walther; Irena Vladimirova; Danai Alexaki; Lea Schäppi; Kathrine S F Damme; Vijay A Mittal; Stewart A Shankman; Katharina Stegmayer
Journal:  J Psychiatr Res       Date:  2021-11-08       Impact factor: 4.791

6.  Diagnosis and neurocognitive profiles in first-episode non-affective psychosis patients.

Authors:  Rosa Ayesa-Arriola; José Manuel Rodríguez-Sánchez; Esther Setién Suero; Lauren E Reeves; Rafael Tabarés-Seisdedos; Benedicto Crespo-Facorro
Journal:  Eur Arch Psychiatry Clin Neurosci       Date:  2016-01-14       Impact factor: 5.270

Review 7.  Movement disorders and psychosis, a complex marriage.

Authors:  Peter N van Harten; P Roberto Bakker; Charlotte L Mentzel; Marina A Tijssen; Diederik E Tenback
Journal:  Front Psychiatry       Date:  2015-01-09       Impact factor: 4.157

8.  Physical Activity in Schizophrenia is Higher in the First Episode than in Subsequent Ones.

Authors:  Sebastian Walther; Katharina Stegmayer; Helge Horn; Nadja Razavi; Thomas J Müller; Werner Strik
Journal:  Front Psychiatry       Date:  2015-01-05       Impact factor: 4.157

9.  The Longitudinal Course of Gross Motor Activity in Schizophrenia - Within and between Episodes.

Authors:  Sebastian Walther; Katharina Stegmayer; Helge Horn; Luca Rampa; Nadja Razavi; Thomas J Müller; Werner Strik
Journal:  Front Psychiatry       Date:  2015-02-05       Impact factor: 4.157

10.  Cerebral white matter structure is associated with DSM-5 schizophrenia symptom dimensions.

Authors:  Petra V Viher; Katharina Stegmayer; Stéphanie Giezendanner; Andrea Federspiel; Stephan Bohlhalter; Tim Vanbellingen; Roland Wiest; Werner Strik; Sebastian Walther
Journal:  Neuroimage Clin       Date:  2016-06-16       Impact factor: 4.881

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