| Literature DB >> 2424435 |
G Pratviel, J Bernadou, B Meunier.
Abstract
KHSO5, a water soluble single oxygen donor, is shown to be capable of activating bleomycin-FeIII complex for DNA cleavage. DNA breaks mediated by bleomycin-FeIII in the presence of H2O2 or KHSO5 are compared and the P450-like activation of metallobleomycins is discussed.Entities:
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Year: 1986 PMID： 2424435 DOI： 10.1016/0006-291x(86)90434-1
Source DB: PubMed Journal: Biochem Biophys Res Commun ISSN： 0006-291X Impact factor: 3.575