Literature DB >> 2424334

Characterization of the in vitro effects of glucocorticosteroids on NK cell activity.

B K Pedersen, J M Beyer.   

Abstract

The NK cell activity of mononuclear cells as well as monocyte-depleted, Percoll-fractionated, NK cell-enriched effector cells against K 562 target cells was inhibited by methylprednisolone (MP) and hydrocortisone (HC) in a dose-dependent manner. The effector/target cell conjugate formation was studied in a single cell agarose assay, and it was shown that MP and HC partly inhibited the NK cell activity by inhibition of the adhesion of effector cells to target.

Entities:  

Mesh：

Substances：

Year:  1986        PMID： 2424334     DOI： 10.1111/j.1398-9995.1986.tb00303.x

Source DB:  PubMed          Journal:  Allergy        ISSN： 0105-4538            Impact factor:   13.146


  5 in total

1.  Human NK Cell Cytoskeletal Dynamics and Cytotoxicity Are Regulated by LIM Kinase.

Authors:  Melody G Duvall; Mary E Fuhlbrigge; Roisin B Reilly; Katherine H Walker; Ayşe Kılıç; Bruce D Levy
Journal:  J Immunol       Date:  2020-07-08       Impact factor: 5.422

2.  Natural killer cell-mediated inflammation resolution is disabled in severe asthma.

Authors:  Melody G Duvall; Cindy Barnig; Manuela Cernadas; Isabell Ricklefs; Nandini Krishnamoorthy; Nicole L Grossman; Nirav R Bhakta; John V Fahy; Eugene R Bleecker; Mario Castro; Serpil C Erzurum; Benjamin M Gaston; Nizar N Jarjour; David T Mauger; Sally E Wenzel; Suzy A Comhair; Andrea M Coverstone; Merritt L Fajt; Annette T Hastie; Mats W Johansson; Michael C Peters; Brenda R Phillips; Elliot Israel; Bruce D Levy
Journal:  Sci Immunol       Date:  2017-03-10

3.  Effects of in vivo hyperthermia on natural killer cell activity, in vitro proliferative responses and blood mononuclear cell subpopulations.

Authors:  M Kappel; C Stadeager; N Tvede; H Galbo; B K Pedersen
Journal:  Clin Exp Immunol       Date:  1991-04       Impact factor: 4.330

4.  Depressed natural killer cell activity in acute myocardial infarction.

Authors:  K Klarlund; B K Pedersen; T G Theander; V Andersen
Journal:  Clin Exp Immunol       Date:  1987-10       Impact factor: 4.330

5.  Corticosteroids inhibit the generation of lymphokine-activated killer activity in vitro.

Authors:  D W McVicar; R E Merchant; L H Merchant; H F Young
Journal:  Cancer Immunol Immunother       Date:  1989       Impact factor: 6.968
  5 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.